Genetic transformation of auxotrophs of the extreme thermophile Thermus thermophilus HB27
to prototrophy was obtained at high frequencies of 10(-2) to 10(-1) when proliferating cell …

A long-term goal of cancer diagnosis is to develop tumor-imaging techniques that have
sufficient specificity and sensitivity. To achieve this goal, minimizing the background signal …

Fibroblast growth factor (FGF) 21, a structural relative of FGF23 that regulates phosphate
homeostasis, is a regulator of insulin-independent glucose transport in adipocytes and plays a …

Purpose To preoperatively and intraoperatively localize the sentinel lymph node (SLN), a
single hybrid probe for MR and near infrared (NIR) optical imaging was synthesized and tested…

Quantum dots can be used to perform multicolor images with high fluorescent intensity and
are of a nanosize suitable for lymphatic imaging via direct interstitial injection. Here …

Current contrast agents generally have one function and can only be imaged in monochrome;
therefore, the majority of imaging methods can only impart uniparametric information. A …

β-Galactosidase is a widely used reporter enzyme, but although several substrates are
available for in vitro detection, its application for in vivo optical imaging remains a challenge. To …

The whole-genome sequencing of an extreme thermophile, Thermus thermophilus, is now
in progress. Like other genome projects, major concern is shifting from the sequence itself to …

Molecular imaging of cell surface receptors can potentially diagnose tumors based on their
distinct expression profiles. Using multifilter spectrally resolved optical imaging with three …

… Yukihiro Hama and Yoshinori Koyama are contributed equally to this work. … Yukihiro
Hama Æ Yoshinori Koyama Æ Yasuteru Urano Æ Peter L. Choyke Æ Hisataka Kobayashi …