Over the past several decades, significant advances have been made in our understanding
of the basic stages and mechanisms of mammalian brain development. Studies elucidating …

Malformations of cortical development are a group of rare disorders commonly manifesting
with developmental delay, cerebral palsy or seizures. The neurological outcome is …

Myelin loss and axonal damage are both observed in white matter injuries. Each may have
significant impact on the long-term disability of patients. Currently, there does not exist a …

Alongside the exponential flourish of research on age-related trajectories of human brain
development during childhood and adolescence in the past two decades, there has been an …

Studying how the healthy human brain develops is important to understand early
pathological mechanisms and to assess the influence of fetal or perinatal events on later life …

Myelin oligodendrocyte glycoprotein (MOG)-associated disease (MOGAD) is a rare,
antibody-mediated inflammatory demyelinating disorder of the central nervous system …

White matter makes up about fifty percent of the human brain. Maturation of white matter
accompanies biological development and undergoes the most dramatic changes during …

Dynamic macrostructural and microstructural changes take place from the mid-fetal stage to
2 years after birth. Delineating structural changes of the brain during early development …

The preschool years represent a time of expansive mental growth, with the initial expression
of many psychological abilities that will continue to be refined into young adulthood …

Magnetic resonance diffusion tensor imaging (DTI) is a non-invasive in vivo method for
characterizing the integrity of anatomical connections and white matter circuitry and provides …