CADASIL and CARASIL are hereditary small vessel diseases leading to vascular dementia.
CADASIL commonly begins with migraine followed by minor strokes in mid‐adulthood …

Cerebral autosomal dominant arteriopathy with subcortical infarcts and
leukoencephalopathy (CADASIL) is a hereditary cerebrovascular disease leading to …

Notch receptors and ligands were first identified in flies and worms, where they were shown
to regulate cell proliferation, cell differentiation, and, in particular, binary cell fate decisions in …

Background and Purpose—White matter (WM) hyperintensities on MRI or leukoaraiosis is
characteristic of stroke syndromes. Increased MRI signals in the anterior temporal pole are …

In cerebral autosomal dominant arteriopathy with subcortical infarcts and leuco‐
encephalopathy (CADASIL) the vascular smooth muscle cells are destroyed and granular …

Cerebral autosomal dominant arteriopathy with subcortical infarcts and
leukoencephalopathy, or CADASIL, is a hereditary cerebral small vessel disease caused by …

Background and Purpose—Cerebral autosomal-dominant arteriopathy with subcortical
infarcts and leukoencephalopathy (CADASIL) causes repeated ischemic attacks leading to …

CADASIL is a generalized angiopathy caused by mutations in NOTCH 3 gene leading to
degeneration and loss of vascular smooth muscle cells (VSMC) in small arteries and …

Background Population-based studies have highlighted a close relationship between
migraine and stroke. Migraine, especially with aura, is a risk factor for both ischemic and …

Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and
Leukoencephalopathy (CADASIL) syndrome is the most common monogenic inherited form …