Pathophysiological changes in the spinal cord white and grey matter resulting from injury
can be observed with MRI techniques. These techniques provide sensitive markers of …

A first-ever spinal cord imaging meeting was sponsored by the International Spinal
Research Trust and the Wings for Life Foundation with the aim of identifying the current state …

Treatment of patients sustaining a complete spinal cord injury remains an unsolved clinical
problem because of the lack of spontaneous regeneration of injured central axons. A 38 …

Numerous studies in animals have shown the unique property of olfactory ensheathing cells
to stimulate regeneration of lesioned axons in the spinal cord. In a Phase I clinical trial, we …

Diffusion tensor imaging (DTI) has been widely applied to investigate injuries in the central
nervous system (CNS) white matter (WM). However, the underlying pathological correlates …

Injured axons of the adult CNS undergo lengthy retraction from the initial site of axotomy
after spinal cord injury. Macrophage infiltration correlates spatiotemporally with this …

Axonal degeneration of white matter fibers is a key consequence of neuronal or axonal
injury. It is characterized by a series of time-related events with initial axonal membrane …

Quantitative MRI measures of multiexponential T2 relaxation and magnetization transfer
were acquired from six samples of excised and fixed rat spinal cord and compared with …

Recent studies have suggested that axonal damage, and not demyelination, is the primary
cause of long‐term neurological impairment in multiple sclerosis and its animal model …

Diffusion tensor imaging (DTI) provides a measure of the directional diffusion of water
molecules in tissues. The measurement of DTI indexes within the spinal cord provides a …