Importance Hypoxic-ischemic encephalopathy (HIE) occurs in 1 to 8 per 1000 live births in
developed countries. Historically, the clinician has had little to offer neonates with HIE other …

Objective To establish the evidence of therapeutic hypothermia for newborns with hypoxic
ischemic encephalopathy (HIE). Data Sources Cochrane Central Register of Controlled …

The thoroughly updated Fourth Edition of this acclaimed reference describes and illustrates
the full range of pediatric disorders diagnosable by modern neuroimaging. This edition …

Objective: Preterm infants are exposed to multiple painful procedures in the neonatal
intensive care unit (NICU) during a period of rapid brain development. Our aim was to …

Background Congenital heart disease in newborns is associated with global impairment in
development. We characterized brain metabolism and microstructure, as measures of brain …

Neonatal hypoxia-ischaemia (HI) is the most common cause of death and disability in
human neonates, and is often associated with persistent motor, sensory, and cognitive …

Background Moderate hypothermia in neonates with hypoxic–ischaemic encephalopathy
might improve survival and neurological outcomes at up to 18 months of age, although …

Successful resuscitation from cardiac arrest results in a post–cardiac arrest syndrome, which
can evolve in the days to weeks after return of sustained circulation. The components of post …

Abstract This Point of View article addresses neonatal encephalopathy (NE) presumably
caused by hypoxia–ischemia and the terminology currently in wide use for this disorder. The …

OBJECTIVE: To determine if multiple doses of erythropoietin (Epo) administered with
hypothermia improve neuroradiographic and short-term outcomes of newborns with hypoxic …