Animal models are necessary to develop and test innovations in aneurysm therapy before
clinical introduction. This review aims at identifying the most likely candidates for …

Animal models make an important contribution to our basic understanding of the
pathobiology of human brain aneurysms, are indispensable in testing novel treatment …

Aneurysmal subarachnoid hemorrhage is a common complication caused by an intracranial
aneurysm that can lead to hemorrhagic stroke, brain damage, and death. Knowing this …

Preclinical studies are important in helping practitioners and device developers improve
techniques and tools for endovascular treatment of intracranial aneurysms. Thus an …

Intracranial aneurysm (IA) animal models are paramount to study IA pathophysiology and to
test new endovascular treatments. A number of in vivo imaging modalities are available to …

BACKGROUND AND PURPOSE: Despite rapid advances in the development of materials
and techniques for endovascular intracranial aneurysm treatment, occlusion of large broad …

Clinical studies suggest that aneurysm aspect ratio (AR) is an important indicator of rupture
likelihood. The importance of AR is hypothesized to arise from its influence on intra …

In modern society, intracranial aneurysms have seriously affected people's life. To better
study and treat intracranial aneurysm, animal models are ideal candidates to perform …

Background: Rabbit models involving neck arteries are of growing importance for the
development of preclinical aneurysm models. An optimal understanding of the anatomy is …

Purpose The elastase-induced aneurysm (EIA) model in rabbits has been proposed for
translational research; however, the adjustment of aneurysm neck size remains challenging …