A narrative review of cancer-related fatigue (CRF) and its possible pathogenesis

S Yang, S Chu, Y Gao, Q Ai, Y Liu, X Li, N Chen - Cells, 2019 - mdpi.com
Many cancer patients suffer from severe fatigue when treated with chemotherapy or
radiotherapy; however, the etiology and pathogenesis of this kind of fatigue remains …

Central pathways causing fatigue in neuro-inflammatory and autoimmune illnesses

G Morris, M Berk, K Walder, M Maes - BMC medicine, 2015 - Springer
Background The genesis of severe fatigue and disability in people following acute pathogen
invasion involves the activation of Toll-like receptors followed by the upregulation of …

Establishing pathological cut-offs of brain atrophy rates in multiple sclerosis

N De Stefano, ML Stromillo, A Giorgio… - Journal of Neurology …, 2016 - jnnp.bmj.com
Objective To assess whether it is feasible to establish specific cut-off values able to
discriminate 'physiological'or 'pathological'brain volume rates in patients with multiple …

Cortical thickness and serum NfL explain cognitive dysfunction in newly diagnosed patients with multiple sclerosis

ÁJ Cruz-Gomez, L Forero, E Lozano-Soto… - Neurology …, 2021 - AAN Enterprises
Background and Objectives To determine the relative importance of global or regional MRI
and blood markers of neurodegeneration and neuroaxonal injury in predicting cognitive …

Multiple sclerosis: altered thalamic resting-state functional connectivity and its effect on cognitive function

F Tona, N Petsas, E Sbardella, L Prosperini… - Radiology, 2014 - pubs.rsna.org
Purpose To investigate, by using resting-state (RS) functional magnetic resonance (MR)
imaging, thalamocortical functional connectivity (FC) and its correlations with cognitive …

Measurement of whole-brain and gray matter atrophy in multiple sclerosis: assessment with MR imaging

L Storelli, MA Rocca, E Pagani, W Van Hecke… - Radiology, 2018 - pubs.rsna.org
Purpose To compare available methods for whole-brain and gray matter (GM) atrophy
estimation in multiple sclerosis (MS) in terms of repeatability (same magnetic resonance …

[HTML][HTML] Gray matters in multiple sclerosis: cognitive impairment and structural MRI

S Messina, F Patti - Multiple sclerosis international, 2014 - Wiley Online Library
Multiple sclerosis (MS) is an immune‐mediated disease affecting central nervous system
(CNS). Although MS is classically considered a white matter (WM) disease, the involvement …

Increased total sodium concentration in gray matter better explains cognition than atrophy in MS

A Maarouf, B Audoin, F Pariollaud, S Gherib, A Rico… - Neurology, 2017 - AAN Enterprises
Objective: To investigate whether brain total sodium accumulation assessed by 23Na MRI is
associated with cognitive deficit in relapsing-remitting multiple sclerosis (RRMS). Methods …

Changes in brain functional connectivity patterns are driven by an individual lesion in MS: a resting-state fMRI study

A Droby, KSL Yuen, M Muthuraman, SC Reitz… - Brain imaging and …, 2016 - Springer
Diffuse inflammation in multiple sclerosis (MS) extends beyond focal lesion sites, affecting
interconnected regions; however, little is known about the impact of an individual lesion …

An interpretable machine learning model to predict cortical atrophy in multiple sclerosis

A Conti, CA Treaba, A Mehndiratta, VT Barletta… - Brain Sciences, 2023 - mdpi.com
To date, the relationship between central hallmarks of multiple sclerosis (MS), such as white
matter (WM)/cortical demyelinated lesions and cortical gray matter atrophy, remains unclear …