Platelets play a fundamental role in normal hemostasis, while their inherited or acquired
dysfunctions are involved in a variety of bleeding disorders or thrombotic events. Several …

Endovascular coiling for intracranial aneurysms has become an accepted treatment with
good clinical results and provides adequate protection against rebleeding and rupture of …

BACKGROUND AND PURPOSE: Ticagrelor is a novel P2Y12 antagonist, and little is known
about its efficacy and safety in the endovascular treatment of aneurysms. This study …

Background and Purpose: This study tests whether patients with unruptured intracranial
aneurysm who underwent stent placement benefitted from platelet function monitoring …

Neuroendovascular techniques for treating cerebral aneurysms and other cerebrovascular
pathology are increasingly becoming the standard of care. Intraluminal stents, aneurysm …

Background Antiplatelet and antithrombotic medication management before, during, and
after neurointerventional procedures has significant practice variation. This document …

Importance Thromboembolism is the most common complication in coiling for an unruptured
aneurysm and is frequent in patients with high on-treatment platelet reactivity (HTPR) who …

BACKGROUND Dual antiplatelet therapy (DAPT) associating aspirin+ clopidogrel is
commonly utilized in neurovascular interventions despite unpredictable clopidogrel efficacy …

Purpose Standard dual antiplatelet therapy (DAPT) for complex aneurysms treated with flow
diversion and flow disruption is acetylsalicylic acid (ASA) plus clopidogrel. However …

Background and purpose Variability in response to clopidogrel therapy is increasingly being
recognized as an important factor in thromboembolic and hemorrhagic complications …