Potential neuroimaging biomarkers of pathologic brain changes in Mild Cognitive Impairment and Alzheimer's disease: a systematic review

Q Ruan, G D'Onofrio, D Sancarlo, Z Bao, A Greco, Z Yu - BMC geriatrics, 2016 - Springer
Abstract Background Neuroimaging-biomarkers of Mild Cognitive Impairment (MCI) allow an
early diagnosis in preclinical stages of Alzheimer's disease (AD). The goal in this paper was …

[HTML][HTML] Structural MR imaging in the diagnosis of Alzheimer's disease and other neurodegenerative dementia: current imaging approach and future perspectives

M Park, WJ Moon - Korean journal of radiology, 2016 - ncbi.nlm.nih.gov
With the rise of aging population, clinical concern and research attention has shifted towards
neuroimaging of dementia. The advent of 3T, magnetic resonance imaging (MRI) has …

[HTML][HTML] Magnetization transfer ratio relates to cognitive impairment in normal elderly

S Seiler, L Pirpamer, E Hofer, M Duering… - Frontiers in aging …, 2014 - frontiersin.org
Magnetization transfer imaging (MTI) can detect microstructural brain tissue changes and
may be helpful in determining age-related cerebral damage. We investigated the …

Demyelination in mild cognitive impairment suggests progression path to Alzheimer's disease

C Carmeli, A Donati, V Antille, D Viceic, J Ghika… - PloS one, 2013 - journals.plos.org
The preclinical Alzheimer's disease (AD)-amnestic mild cognitive impairment (MCI)-is
manifested by phenotypes classified into exclusively memory (single-domain) MCI (sMCI) …

Magnetization transfer imaging for in vivo detection of microstructural tissue changes in aging and dementia: a short literature review

S Seiler, S Ropele, R Schmidt - Journal of Alzheimer's …, 2014 - content.iospress.com
Abstract Magnetization-transfer imaging (MTI), a magnetic resonance imaging acquisition
protocol, can detect microstructural brain tissue changes by assessing the magnetization …

Magnetization transfer MRI in dementia disorders, Huntington's disease and parkinsonism

N Tambasco, P Nigro, M Romoli, S Simoni… - Journal of the …, 2015 - Elsevier
Magnetic resonance imaging is the most used technique of neuroimaging. Using recent
advances in magnetic resonance application it is possible to investigate several changes in …

Saturation transfer MRI for detection of metabolic and microstructural impairments underlying neurodegeneration in alzheimer's disease

A Orzyłowska, W Oakden - Brain Sciences, 2021 - mdpi.com
Alzheimer's disease (AD) is one of the most common causes of dementia and difficult to
study as the pool of subjects is highly heterogeneous. Saturation transfer (ST) magnetic …

Regional analysis of the magnetization transfer ratio of the brain in mild Alzheimer disease and amnestic mild cognitive impairment

M Mascalchi, A Ginestroni, V Bessi… - American Journal …, 2013 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Manually drawn VOI-based analysis shows a decrease in
magnetization transfer ratio in the hippocampus of patients with Alzheimer disease. We …

Gender, age‐related, and regional differences of the magnetization transfer ratio of the cortical and subcortical brain gray matter

M Mascalchi, N Toschi, A Ginestroni… - Journal of Magnetic …, 2014 - Wiley Online Library
Purpose To explore gender, age‐related, and regional differences of magnetization transfer
ratio (MTR) of brain cortical and subcortical gray matter (GM). Materials and Methods In all …

[HTML][HTML] Model-Based Magnetization Transfer imaging Markers to characterize Patients and asymptomatic gene carriers in huntington's Disease

R Wiest, JM Burgunder, C Kiefer - Frontiers in neurology, 2017 - frontiersin.org
Background and purpose Huntington's disease (HD) is a chronic progressive
neurodegenerative disorder with a long presymptomatic period that opens a window for …