Thrombus composition and efficacy of thrombolysis and thrombectomy in acute ischemic stroke

P Jolugbo, RAS Ariëns - Stroke, 2021 - Am Heart Assoc
Thrombi retrieved from patients with acute ischemic stroke are highly heterogeneous.
Recent data suggest that thrombus composition may impact on mechanical thrombectomy …

Diagnosis and management of acute ischaemic stroke

R Hurford, A Sekhar, TAT Hughes, KW Muir - Practical Neurology, 2020 - pn.bmj.com
Acute ischaemic stroke is a major public health priority and will become increasingly
relevant to neurologists of the future. The cornerstone of effective stroke care continues to be …

Imaging features and safety and efficacy of endovascular stroke treatment: a meta-analysis of individual patient-level data

L San Román, BK Menon, J Blasco… - The Lancet …, 2018 - thelancet.com
Background Evidence regarding whether imaging can be used effectively to select patients
for endovascular thrombectomy (EVT) is scarce. We aimed to investigate the association …

Association of clinical, imaging, and thrombus characteristics with recanalization of visible intracranial occlusion in patients with acute ischemic stroke

BK Menon, FS Al-Ajlan, M Najm, J Puig, M Castellanos… - Jama, 2018 - jamanetwork.com
Importance Recanalization of intracranial thrombus is associated with improved clinical
outcome in patients with acute ischemic stroke. The association of intravenous alteplase …

Incidence and predictors of early recanalization after intravenous thrombolysis: a systematic review and meta-analysis

P Seners, G Turc, B Maïer, JL Mas, C Oppenheim… - Stroke, 2016 - Am Heart Assoc
Background and Purpose—After the demonstration of efficacy of bridging therapy, reliably
predicting early recanalization (ER;≤ 3 hours after start of intravenous thrombolysis) would …

Thrombus imaging characteristics and outcomes in acute ischemic stroke patients undergoing endovascular treatment

BG Dutra, ML Tolhuisen, HCBR Alves, KM Treurniet… - Stroke, 2019 - Am Heart Assoc
Background and Purpose—Thrombus imaging characteristics have been reported to be
useful to predict functional outcome and reperfusion in acute ischemic stroke. However …

Revolution in acute ischaemic stroke care: a practical guide to mechanical thrombectomy

MRB Evans, P White, P Cowley, DJ Werring - Practical neurology, 2017 - pn.bmj.com
Rapid, safe and effective arterial recanalisation to restore blood flow and improve functional
outcome remains the primary goal of hyperacute ischaemic stroke management. The benefit …

Analyses of thrombi in acute ischemic stroke: a consensus statement on current knowledge and future directions

SF De Meyer, T Andersson, B Baxter… - … journal of stroke, 2017 - journals.sagepub.com
Limited data exist on clot composition and detailed characteristics of arterial thrombi
associated with large vessel occlusion in acute ischemic stroke. Advances in endovascular …

Role of imaging in current acute ischemic stroke workflow for endovascular therapy

BK Menon, BCV Campbell, C Levi, M Goyal - Stroke, 2015 - Am Heart Assoc
Ischemic stroke is caused by a thrombus that blocks an intracranial artery. Brain tissue
beyond the blocked artery survives for a variable period of time because of blood and …

Bridging therapy or IV thrombolysis in minor stroke with large vessel occlusion

P Seners, C Perrin, B Lapergue, H Henon… - Annals of …, 2020 - Wiley Online Library
Objective Whether bridging therapy (intravenous thrombolysis [IVT] followed by
endovascular treatment) is superior to IVT alone in minor stroke with large vessel occlusion …