Since the discovery of sickle cell disease (SCD) in 1910, enormous strides have been made
in the elucidation of the pathogenesis of its protean complications, which has inspired recent …

Introduction: Over the past decades, neuroimaging studies have clarified that a significant
proportion of patients with sickle cell disease (SCD) have functionally significant brain …

Sickle cell anaemia (SCA) is a hereditary hemoglobinopathy characterised by extensive
vascular dysfunction that stems from inflammation, thrombosis and occlusion of post …

Sickle cell disease is a common, inherited disordered characterized by chronic hemolytic
anemia with repetitive episodes of vasoocclusion resulting from deformed red blood cells …

Background Extraction of liver parenchyma is an important step in the evaluation of‐based
hepatic iron content (HIC). Traditionally, this is performed by radiologists via whole‐liver …

Microhemorrhages in cerebral and cerebellar parenchyma are due to various underlying
causes. Conventional MR imaging sequences and CT are often not sufficient for their …

Background: Sickle cell disease (SCD) is an autosomal recessive hemolytic disorder; its
cerebrovascular complications include silent cerebral ischemia, infarct, and brain atrophy …

Background and Purpose Conventional magnetic resonance imaging (MRI) of patients with
hemolytic uremic syndrome (HUS) and neurological symptoms performed during an …

In this paper a method is presented to enable automatic classification of the degree of
abnormality of susceptibility-weighted images (SWI) acquired from babies with hypoxic …

Iron metabolism in humans is essentially conservative, so that once excess iron has
accumulated in the body, it can only be removed by phlebotomy or with iron chelators. In …