Air pollution, stress, and allostatic load: linking systemic and central nervous system impacts

EM Thomson - Journal of Alzheimer's Disease, 2019 - content.iospress.com
Air pollution is a risk factor for cardiovascular and respiratory morbidity and mortality. A
growing literature also links exposure to diverse air pollutants (eg, nanoparticles, particulate …

Glucocorticoids and cognitive function: a walkthrough in endogenous and exogenous alterations

D De Alcubierre, D Ferrari, G Mauro, AM Isidori… - Journal of …, 2023 - Springer
Purpose The hypothalamic–pituitary–adrenal (HPA) axis exerts many actions on the central
nervous system (CNS) aside from stress regulation. Glucocorticoids (GCs) play an important …

Circulating cortisol and cognitive and structural brain measures: The Framingham Heart Study

JB Echouffo-Tcheugui, SC Conner, JJ Himali… - Neurology, 2018 - AAN Enterprises
Objective To assess the association of early morning serum cortisol with cognitive
performance and brain structural integrity in community-dwelling young and middle-aged …

Association between use of systemic and inhaled glucocorticoids and changes in brain volume and white matter microstructure: a cross-sectional study using data …

M van der Meulen, JM Amaya, OM Dekkers… - BMJ open, 2022 - bmjopen.bmj.com
Objective To test the hypothesis that systemic and inhaled glucocorticoid use is associated
with changes in grey matter volume (GMV) and white matter microstructure. Design Cross …

Psychiatric and neurocognitive consequences of endogenous hypercortisolism

M Piasecka, E Papakokkinou, E Valassi… - Journal of internal …, 2020 - Wiley Online Library
Psychiatric and neurocognitive symptoms due to hypercortisolism were already described
by Harvey Cushing in his original paper on patients with Cushing's syndrome (CS) …

Effects of long-term endogenous corticosteroid exposure on brain volume and glial cells in the AdKO mouse

JM Amaya, E Suidgeest, I Sahut-Barnola… - Frontiers in …, 2021 - frontiersin.org
Chronic exposure to high circulating levels of glucocorticoids has detrimental effects on
health, including metabolic abnormalities, as exemplified in Cushing's syndrome (CS) …

[HTML][HTML] Stress hormones as potential mediators of air pollutant effects on the brain: rapid induction of glucocorticoid-responsive genes

EM Thomson, A Filiatreault, J Guénette - Environmental research, 2019 - Elsevier
Air pollution is associated with adverse effects on brain health including cognitive decline,
dementia, anxiety, depression, and suicide. While toxicological studies have demonstrated …

Quality of life in patients with Cushing's disease

A Santos, E Resmini, MA Martínez Momblán… - Frontiers in …, 2019 - frontiersin.org
Cushing's disease (and by extension, Cushing's syndrome) is a rare disease due to a
chronic cortisol excess, which usually has an important impact on quality of life (QoL). It can …

Comorbidity of osteoporosis and Alzheimer's disease: IsAKT-ing on cellular glucose uptake the missing link?

K Fehsel, J Christl - Ageing Research Reviews, 2022 - Elsevier
Osteoporosis and Alzheimer's disease (AD) are both degenerative diseases. Osteoporosis
often proceeds cognitive deficits, and multiple studies have revealed common triggers that …

Gut feelings: the microbiota-gut-brain axis on steroids

SY So, TC Savidge - American Journal of Physiology …, 2022 - journals.physiology.org
The intricate connection between central and enteric nervous systems is well established
with emerging evidence linking gut microbiota function as a significant new contributor to gut …