Challenges in the diagnosis of Parkinson's disease

E Tolosa, A Garrido, SW Scholz, W Poewe - The Lancet Neurology, 2021 - thelancet.com
Parkinson's disease is the second most common neurodegenerative disease and its
prevalence has been projected to double over the next 30 years. An accurate diagnosis of …

Systematic review: quantitative susceptibility mapping (QSM) of brain iron profile in neurodegenerative diseases

P Ravanfar, SM Loi, WT Syeda… - Frontiers in …, 2021 - frontiersin.org
Iron has been increasingly implicated in the pathology of neurodegenerative diseases. In
the past decade, development of the new magnetic resonance imaging technique …

Imaging the substantia nigra in Parkinson disease and other Parkinsonian syndromes

YJ Bae, JM Kim, CH Sohn, JH Choi, BS Choi, YS Song… - Radiology, 2021 - pubs.rsna.org
Parkinson disease is characterized by dopaminergic cell loss in the substantia nigra of the
midbrain. There are various imaging markers for Parkinson disease. Recent advances in …

Overview of quantitative susceptibility mapping

A Deistung, F Schweser… - NMR in …, 2017 - Wiley Online Library
Magnetic susceptibility describes the magnetizability of a material to an applied magnetic
field and represents an important parameter in the field of MRI. With the recently introduced …

Clinical quantitative susceptibility mapping (QSM): biometal imaging and its emerging roles in patient care

Y Wang, P Spincemaille, Z Liu, A Dimov… - Journal of magnetic …, 2017 - Wiley Online Library
Quantitative susceptibility mapping (QSM) has enabled magnetic resonance imaging (MRI)
of tissue magnetic susceptibility to advance from simple qualitative detection of hypointense …

[HTML][HTML] Multimodal comparisons of QSM and PET in neurodegeneration and aging

PM Cogswell, AP Fan - NeuroImage, 2023 - Elsevier
Quantitative susceptibility mapping (QSM) has been used to study susceptibility changes
that may occur based on tissue composition and mineral deposition. Iron is a primary …

Quantitative susceptibility mapping in Parkinson's disease

C Langkammer, L Pirpamer, S Seiler, A Deistung… - PLoS …, 2016 - journals.plos.org
Background Quantitative susceptibility mapping (QSM) and R2* relaxation rate mapping
have demonstrated increased iron deposition in the substantia nigra of patients with …

Meta-analysis of brain iron levels of Parkinson's disease patients determined by postmortem and MRI measurements

JY Wang, QQ Zhuang, LB Zhu, H Zhu, T Li, R Li… - Scientific reports, 2016 - nature.com
Brain iron levels in patients of Parkinson's disease (PD) are usually measured in
postmortem samples or by MRI imaging including R2* and SWI. In this study we performed a …

Colocalization of cerebral iron with amyloid beta in mild cognitive impairment

JMG Van Bergen, X Li, J Hua, SJ Schreiner… - Scientific reports, 2016 - nature.com
Abstract Quantitative Susceptibility Mapping (QSM) MRI at 7 Tesla and 11-Carbon
Pittsburgh-Compound-B PET were used for investigating the relationship between brain iron …

Quantitative susceptibility mapping: contrast mechanisms and clinical applications

C Liu, H Wei, NJ Gong, M Cronin, R Dibb, K Decker - Tomography, 2015 - mdpi.com
Quantitative susceptibility mapping (QSM) is a recently developed magnetic resonance
imaging (MRI) technique for quantifying the spatial distribution of magnetic susceptibility …