Endovascular treatment of intracranial aneurysms (IAs) has evolved considerably over the
past decades. The technological advances have been driven by the experience that coils fail …

BACKGROUND: The implantation of flow-diverter stents for the treatment of ruptured
intracranial aneurysms required further investigation. PURPOSE: Our aim was to analyze …

OBJECTIVE Flow diversion requires neointimal stent overgrowth to deliver aneurysm
occlusion. The existing literature on aneurysm occlusion is limited by heterogeneous follow …

Flow diversion has become a well-accepted option for the treatment of cerebral aneurysms.
Given the significant treatment effect of flow diverters, numerous options have emerged …

BACKGROUND The safety and efficacy of the first generation of the Pipeline Embolization
Device (PED; Medtronic Inc) have been proven in large case series. Ischemic events are …

The cost of clinical trials is ever-increasing. In-silico trials rely on virtual populations and
interventions simulated using patient-specific models and may offer a solution to lower these …

Background Flow diverter stents (FDS) are a recognized treatment option for intracranial
aneurysms. There remain ongoing concerns regarding the safety of FDS, especially …

Background The first and second generations of the Pipeline Embolization Device (PED)
have been widely adopted for the treatment of intracranial aneurysms (IAs) due to their high …

Uptake of flow-diverting technology is rapidly outpacing the availability of clinical evidence.
Most current usage is off-label, and the endovascular community is nearer the beginning …

During intracranial aneurysm embolization with the Pipeline embolization device (PED),
ischemic and hemorrhagic complications have been observed in cases among Western …