Immune cell Membrane‐Coated biomimetic nanoparticles for targeted cancer therapy
Nanotechnology has provided great opportunities for managing neoplastic conditions at
various levels, from preventive and diagnostic to therapeutic fields. However, when it comes …
various levels, from preventive and diagnostic to therapeutic fields. However, when it comes …
The peritumoral brain zone in glioblastoma: Where we are and where we are going
M Giambra, A Di Cristofori, S Valtorta… - Journal of …, 2023 - Wiley Online Library
Glioblastoma (GBM) is the most aggressive and invasive primary brain tumor. Current
therapies are not curative, and patients' outcomes remain poor with an overall survival of …
therapies are not curative, and patients' outcomes remain poor with an overall survival of …
Detection of tissue pH with quantitative chemical exchange saturation transfer magnetic resonance imaging
Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) has
emerged as a novel means for sensitive detection of dilute labile protons and chemical …
emerged as a novel means for sensitive detection of dilute labile protons and chemical …
[HTML][HTML] Targeting immunometabolism in glioblastoma
AA Mohan, WH Tomaszewski… - Frontiers in …, 2021 - frontiersin.org
We have only recently begun to understand how cancer metabolism affects antitumor
responses and immunotherapy outcomes. Certain immunometabolic targets have been …
responses and immunotherapy outcomes. Certain immunometabolic targets have been …
[HTML][HTML] Fast and equilibrium CEST imaging of brain tumor patients at 3T
Chemical exchange saturation transfer (CEST) MRI, versatile for detecting endogenous
mobile proteins and tissue pH, has proved valuable in tumor imaging. However, CEST MRI …
mobile proteins and tissue pH, has proved valuable in tumor imaging. However, CEST MRI …
[HTML][HTML] Molecular imaging of brain tumors and drug delivery using CEST MRI: promises and challenges
Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) detects
molecules in their natural forms in a sensitive and non-invasive manner. This makes it a …
molecules in their natural forms in a sensitive and non-invasive manner. This makes it a …
High‐sensitivity CEST mapping using a spatiotemporal correlation‐enhanced method
L Chen, S Cao, RC Koehler… - Magnetic resonance in …, 2020 - Wiley Online Library
Purpose To obtain high‐sensitivity CEST maps by exploiting the spatiotemporal correlation
between CEST images. Methods A postprocessing method accomplished by multilinear …
between CEST images. Methods A postprocessing method accomplished by multilinear …
Mathematical modeling of glioma invasion: acid-and vasculature mediated go-or-grow dichotomy and the influence of tissue anisotropy
M Conte, C Surulescu - Applied Mathematics and Computation, 2021 - Elsevier
Starting from kinetic transport equations and subcellular dynamics we deduce a multiscale
model for glioma invasion relying on the go-or-grow dichotomy and the influence of …
model for glioma invasion relying on the go-or-grow dichotomy and the influence of …
Amine‐weighted chemical exchange saturation transfer magnetic resonance imaging in brain tumors
Amine‐weighted chemical exchange saturation transfer (CEST) magnetic resonance
imaging (MRI) is particularly valuable as an amine‐and pH‐sensitive imaging technique in …
imaging (MRI) is particularly valuable as an amine‐and pH‐sensitive imaging technique in …
Activity of a first-in-class oral HIF2-alpha inhibitor, PT2385, in patients with first recurrence of glioblastoma
Introduction Hypoxia inducible factor 2-alpha (HIF2α) mediates cellular responses to
hypoxia and is over-expressed in glioblastoma (GBM). PT2385 is an oral HIF2α inhibitor …
hypoxia and is over-expressed in glioblastoma (GBM). PT2385 is an oral HIF2α inhibitor …