Aging-induced pathological alterations of the circulatory system play a critical role in
morbidity and mortality of older adults. While the importance of cellular and molecular …

Alzheimer's disease (AD) is a neurodegenerative disease that affects brain cells, and mild
cognitive impairment (MCI) has been defined as the early phase that describes the onset of …

Insurmountable evidence has demonstrated a strong association between Alzheimer's
disease (AD) and cerebral amyloid angiopathy (CAA), along with various other …

Deep medullary veins (DMVs) participate in the drainage of surrounding white matter. In
cerebral small vessel disease (CSVD), disrupted DMVs were often observed together with …

Background and Objectives Magnetic resonance susceptibility-weighted imaging (SWI) can
identify small brain blood vessels that contain deoxygenated blood due to its induced …

Cerebral small vessel disease (SVD) is a major cause of stroke and cognitive impairment.
However, the underlying mechanisms behind SVD are still poorly understood. High cerebral …

Background There is a significant increase in the parenchymal microvessel blood volume in
the earliest forms of multiple sclerosis (MS) which may be due to venular dilatation …

Purpose To develop 3D MRI methods for cerebral blood volume (CBV) and venous cerebral
blood volume (vCBV) estimation with whole‐brain coverage using Fourier transform–based …

The etiology of multiple sclerosis (MS) is currently understood to be autoimmune. However,
there is a long history and growing evidence for disrupted vasculature and flow within the …

Cerebral small vessel disease (CSVD) results in a spectrum of neurologic, behavioral, and
cognitive sequelae, most commonly from white matter hyperintensities (WMH) of presumed …