Links between cognitive impairment in insulin resistance: an explanatory model

A Convit - Neurobiology of aging, 2005 - Elsevier
Cognitive function and peripheral glucose regulation both decrease with age. There is a
consistent and growing literature reporting memory and other cognitive problems among …

Impact of metabolic syndrome on cognition and brain: a selected review of the literature

…, PL Yau, MM Turchiano, A Convit - … , and vascular biology, 2012 - Am Heart Assoc
Metabolic syndrome (MetS), a clustering of risk factors for type 2 diabetes mellitus and
cardiovascular disease, has been associated with cognitive dysfunction and brain abnormalities. …

Volumetric analysis of the pre-frontal regions: findings in aging and schizophrenia

A Convit, OT Wolf, MJ de Leon, M Patalinjug… - Psychiatry Research …, 2001 - Elsevier
Frontal lobe dysfunction is thought to be involved in schizophrenia and age-associated cognitive
decline. Frontal lobe volume changes have been investigated in these conditions using …

Prediction of cognitive decline in normal elderly subjects with 2-[18F]fluoro-2-deoxy-d-glucose/positron-emission tomography (FDG/PET)

MJ De Leon, A Convit, OT Wolf… - Proceedings of the …, 2001 - National Acad Sciences
Neuropathology studies show that patients with mild cognitive impairment (MCI) and
Alzheimer's disease typically have lesions of the entorhinal cortex (EC), hippocampus (Hip), and …

Cortisol levels during human aging predict hippocampal atrophy and memory deficits

SJ Lupien, M De Leon, S De Santi, A Convit… - Nature …, 1998 - nature.com
Elevated glucocorticoid levels produce hippocampal dysfunction and correlate with individual
deficits in spatial learning in aged rats. Previously we related persistent cortisol increases …

Dissociation of cognitive and emotional empathy in adults with Asperger syndrome using the Multifaceted Empathy Test (MET)

…, HR Heekeren, OT Wolf, A Convit - Journal of autism and …, 2008 - Springer
Empathy is a multidimensional construct consisting of cognitive (inferring mental states) and
emotional (empathic concern) components. Despite a paucity of research, individuals on the …

[HTML][HTML] The histological validation of post mortem magnetic resonance imaging-determined hippocampal volume in Alzheimer's disease

M Bobinski, MJ De Leon, J Wegiel, S Desanti, A Convit… - Neuroscience, 1999 - Elsevier
For 11 AD cases and four normal elderly controls, post mortem volumes of the hippocampal
subdivisions were calculated by using magnetic resonance imaging and histological …

[HTML][HTML] Specific hippocampal volume reductions in individuals at risk for Alzheimer's disease

A Convit, MJ De Leon, C Tarshish, S De Santi… - Neurobiology of …, 1997 - Elsevier
Our goal was to ascertain the involvement of the temporal lobe in the preclinical (not yet
diagnosable) stages of dementia of the Alzheimer’s type (DAT) by using MRI-derived volumes. …

Hippocampal formation glucose metabolism and volume losses in MCI and AD

S De Santi, MJ de Leon, H Rusinek, A Convit… - Neurobiology of …, 2001 - Elsevier
We used MRI volume sampling with coregistered and atrophy corrected FDG-PET scans to
test three hypotheses: 1) hippocampal formation measures are superior to temporal …

Frequency of hippocampal formation atrophy in normal aging and Alzheimer's disease

…, AE George, J Golomb, C Tarshish, A Convit… - Neurobiology of …, 1997 - Elsevier
We used CT and MR to examine the frequency of occurrence of hippocampal formation atrophy
(HA) in a research clinic population of 130 normal elderly, 72 nondemented patients with …