Importance A key factor in assessing the effectiveness and cost-effectiveness of antiretroviral
therapy (ART) as a prevention strategy is the absolute risk of HIV transmission through …

Early activation and coordination of innate defenses are critical for effective responses against
infiltrating pathogens. Rapid engagement of immune cells provides a critical first line of …

Studies of cellular apoptosis have been significantly impacted since the introduction of flow
cytometry-based methods. Propidium iodide (PI) is widely used in conjunction with Annexin …

Fibroblast-activation protein (FAP) is a serine protease classified in the dipeptidyl peptidase
4 (DPP4) family. FAP is predominantly expressed in activated fibroblasts such as the cancer-…

A common denominator among the multiple damage-inducing agents that ultimately lead to
activation of NLRP3 has not yet been identified. Recently, production of reactive oxygen …

Inflammasomes are multiprotein signaling platforms that form upon sensing microbe-or
damage-associated molecular patterns. Upon their formation, caspase-1 is activated, leading to …

The first aim of this study was to compare an ambulatory five-lead ECG system with the
commercially available breast belt measuring devices; Polar S810i and Suunto t6, in terms of R–…

Background : Although human mesenchymal stem cells (hMSCs) have been tested in
ischemic cardiomyopathy, few studies exist in chronic nonischemic dilated cardiomyopathy (…

Human epidermal Langerhans cells (LC) bearing IgE are found in disease states associated
with hyperimmunoglobulinemia E. When studying the mechanism(s) underlying this …

Background: Abacavir/lamivudine and tenofovir/emtricitabine fixed-dose combinations are
commonly used first-line antiretroviral therapies, yet few studies have comprehensively …