User profiles for A. Buchan

Alastair Buchan

- Verified email at medsci.ox.ac.uk - Cited by 51008

Alison Buchan

- Verified email at utk.edu - Cited by 7544

Glial and neuronal control of brain blood flow

D Attwell, AM Buchan, S Charpak, M Lauritzen… - Nature, 2010 - nature.com
Blood flow in the brain is regulated by neurons and astrocytes. Knowledge of how these
cells control blood flow is crucial for understanding how neural computation is powered, for …

Master recyclers: features and functions of bacteria associated with phytoplankton blooms

A Buchan, GR LeCleir, CA Gulvik… - Nature Reviews …, 2014 - nature.com
Marine phytoplankton blooms are annual spring events that sustain active and diverse
bloom-associated bacterial populations. Blooms vary considerably in terms of eukaryotic species …

Overview of the Marine Roseobacter Lineage

A Buchan, JM González, MA Moran - Applied and environmental …, 2005 - Am Soc Microbiol
Buchan, A., EL Neidle, and MA Moran. 2001. Diversity of the ring-cleaving dioxygenase
gene pcaH in a salt marsh bacterial community. … Buchan, JA Fuhrman, RP Kiene, and MA …

Why are stroke patients excluded from TPA therapy? An analysis of patient eligibility

…, J Zhang, AM Demchuk, MD Hill, AM Buchan - Neurology, 2001 - AAN Enterprises
Background: Thrombolytic therapy for acute stroke (<3 hours) will not have a major impact
on death and dependency unless it is accessible to more patients. Objective: To determine …

Capillary pericytes regulate cerebral blood flow in health and disease

…, A Mishra, BA Sutherland, FM O'Farrell, AM Buchan… - Nature, 2014 - nature.com
Increases in brain blood flow, evoked by neuronal activity, power neural computation and
form the basis of BOLD (blood-oxygen-level-dependent) functional imaging. Whether blood …

Use of the Alberta Stroke Program Early CT Score (ASPECTS) for assessing CT scans in patients with acute stroke

…, ME Hudon, WY Hu, AM Buchan - American Journal …, 2001 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Clinicians are insecure reading CT scans by using the
one-third rule for acute middle cerebral artery stroke (1/3 MCA rule) before treating patients with …

[HTML][HTML] Genome sequence of Silicibacter pomeroyi reveals adaptations to the marine environment

MA Moran, A Buchan, JM González, JF Heidelberg… - Nature, 2004 - nature.com
Since the recognition of prokaryotes as essential components of the oceanic food web 1 ,
bacterioplankton have been acknowledged as catalysts of most major biogeochemical …

Hypothermia but not the N-methyl-D-aspartate antagonist, MK-801, attenuates neuronal damage in gerbils subjected to transient global ischemia

A Buchan, WA Pulsinelli - Journal of Neuroscience, 1990 - Soc Neuroscience
Several laboratories have reported a significant reduction of ischemia- induced injury to
hippocampal neurons in rodents treated with competitive and noncompetitive N-methyl-D-…

Thrombolysis for acute ischemic stroke: results of the Canadian Alteplase for Stroke Effectiveness Study

MD Hill, AM Buchan - Cmaj, 2005 - Can Med Assoc
Background: Thrombolysis for acute ischemic stroke has remained controversial. The
Canadian Alteplase for Stroke Effectiveness Study, a national prospective cohort study, was …

Ecological genomics of marine Roseobacters

…, LS Thompson, E Saunders, A Buchan - Applied and …, 2007 - Am Soc Microbiol
Bacterioplankton of the marine Roseobacter clade have genomes that reflect a dynamic
environment and diverse interactions with marine plankton. Comparative genome sequence …