Chronic subdural haematoma (CSDH) is one of the most common neurological disorders,
and is especially prevalent among elderly individuals. Surgical evacuation is the mainstay of …

Cryo-electron microscopy (cryo-EM) of non-crystalline single particles is a biophysical
technique that can be used to determine the structure of biological macromolecules and …

We consider how to optimize memory use and computation time in operating a quantum
computer. In particular, we estimate the number of memory quantum bits (qubits) and the …

Despite considerable advances in the treatment of multiple myeloma (MM) in the last decade,
a substantial proportion of patients do not respond to current therapies or have a short …

Background Teclistamab is a T-cell–redirecting bispecific antibody that targets both CD3
expressed on the surface of T cells and B-cell maturation antigen expressed on the surface of …

Background New treatment options are needed for patients with multiple myeloma that is
refractory to proteasome inhibitors and immunomodulatory drugs. We assessed daratumumab, …

We performed massively parallel sequencing of paired tumor/normal samples from 203
multiple myeloma (MM) patients and identified significantly mutated genes and copy number …

Lenalidomide, bortezomib, and dexamethasone (RVd) followed by autologous stem cell
transplantation (ASCT) is standard frontline therapy for transplant-eligible patients with newly …

Background Selinexor, a selective inhibitor of nuclear export compound that blocks exportin
1 (XPO1) and forces nuclear accumulation and activation of tumor suppressor proteins, …

Single-particle electron cryo-microscopy (cryo-EM) is a powerful method for solving the three-dimensional
structures of biological macromolecules. The technological development of …