Glucose homeostasis is physiologically maintained by the balance between glucose
production by the liver and glucose utilization by the peripheral tissues. Insulin controls hepatic …

Glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are an important class of drugs
with a well‐established efficacy and safety profile in patients with type 2 diabetes mellitus. …

Cerebral ischemia is caused by arterial occlusion due to a thrombus or an embolus. Such
occlusion induces multiple and concomitant pathophysiological processes that involve …

Schizophrenia has a heritability of 60–80% 1 , much of which is attributable to common risk
alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with …

Background Regulatory guidance specifies the need to establish cardiovascular safety of
new diabetes therapies in patients with type 2 diabetes in order to rule out excess …

Background—Diabetes mellitus (DM) is associated with enhanced lipid peroxidation and
persistent platelet activation. We tested the hypothesis that the in vivo formation of the F 2 -…

Background Whether thrombectomy alone is equally as effective as intravenous alteplase
plus thrombectomy remains controversial. We aimed to determine whether thrombectomy …

Importance The benefits of endovascular revascularization using the contact aspiration
technique vs the stent retriever technique in patients with acute ischemic stroke remain uncertain …

Metformin is a biguanide that has been shown to effectively lower plasma glucose levels in
subjects with noninsulin-dependent diabetes mellitus (NIDDM). However, its mechanism of …

Modern pulsewidth modulation (PWM) inverter motor drives are affected by dangerous
common-mode currents due to the high rate of variation of the modulated voltage. An inexpensive …