User profiles for A. Desjardins

Adrien Desjardins

- Verified email at ucl.ac.uk - Cited by 7669

Audrey Desjardins

- Verified email at uw.edu - Cited by 2821

Fumonisins, mycotoxins produced by Fusarium species: biology, chemistry, and significance

PE Nelson, AE Desjardins… - Annual review of …, 1993 - annualreviews.org
Mycotoxins are secondary metabolites of fungi that are harmful to both animals and humans.
Mycotoxicoses are diseases caused by the ingestion of foods or feeds made toxic by these …

Molecular biology of Fusarium mycotoxins

AE Desjardins, RH Proctor - International journal of food microbiology, 2007 - Elsevier
As the 20th century ended, Fusarium mycotoxicology entered the age of genomics. With
complete genomes of Fusarium graminearum and F. verticillioides and several Fusarium gene …

Trichothecene biosynthesis in Fusarium species: chemistry, genetics, and significance

AE Desjardins, TM Hohn… - Microbiological …, 1993 - Am Soc Microbiol
Several species of the genus Fusarium and related fungi produce trichothecenes which are
sesquiterpenoid epoxides that act as potent inhibitors of eukaryotic protein synthesis. …

Bevacizumab plus irinotecan in recurrent glioblastoma multiforme

JJ Vredenburgh, A Desjardins, JE Herndon… - Journal of clinical …, 2007 - ascopubs.org
Purpose The prognosis for patients with recurrent glioblastoma multiforme is poor, with a
median survival of 3 to 6 months. We performed a phase II trial of bevacizumab, a monoclonal …

Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma

JJ Vredenburgh, A Desjardins, JE Herndon… - Clinical cancer …, 2007 - AACR
Purpose: Recurrent grade III-IV gliomas have a dismal prognosis with minimal improvements
in survival seen following currently available salvage therapy. This study was conducted to …

Co-expression of 15 contiguous genes delineates a fumonisin biosynthetic gene cluster in Gibberella moniliformis

…, DW Brown, RD Plattner, AE Desjardins - Fungal Genetics and …, 2003 - Elsevier
Fumonisins are mycotoxins produced by the maize pathogen Gibberella moniliformis and are
associated with cancer in rodents. In this study, we determined the nucleotide sequence of …

[BOOK][B] Fusarium mycotoxins: chemistry, genetics, and biology.

AE Desjardins - 2006 - cabdirect.org
This book which contains 6 chapters provides a general introduction on mycotoxins, their
discovery, toxicity and evolution, and mycotoxin risk assessment. Part 1 comprises Chapters 1 …

Recurrent glioblastoma treated with recombinant poliovirus

A Desjardins, M Gromeier, JE Herndon… - … England Journal of …, 2018 - Mass Medical Soc
Background The prognosis of patients with recurrent World Health Organization (WHO) grade
IV malignant glioma is dismal, and there is currently no effective therapy. We conducted a …

Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients

…, KL Congdon, EA Reap, GE Archer, A Desjardins… - Nature, 2015 - nature.com
After stimulation, dendritic cells (DCs) mature and migrate to draining lymph nodes to induce
immune responses 1 . As such, autologous DCs generated ex vivo have been pulsed with …

Democratizing technology: pleasure, utility and expressiveness in DIY and maker practice

TJ Tanenbaum, AM Williams, A Desjardins… - Proceedings of the …, 2013 - dl.acm.org
DIY, hacking, and craft have recently drawn attention in HCI and CSCW, largely as a collaborative
and creative hobbyist practice. We shift the focus from the recreational elements of this …