Hypometabolism exceeds atrophy in presymptomatic early-onset familial Alzheimer's disease

…, PS Myoung, W Tsui, A Ginestroni… - Journal of Nuclear …, 2006 - Soc Nuclear Med
The aim of the present study is to compare brain atrophy with hypometabolism as preclinical
markers of Alzheimer's disease (AD) by studying presymptomatic individuals from families …

Axial diffusivity is increased in the degenerating superior cerebellar peduncles of Friedreich's ataxia

R Della Nave, A Ginestroni, S Diciotti, E Salvatore… - Neuroradiology, 2011 - Springer
Introduction Decreased fractional anisotropy (FA) demonstrated by diffusion tensor MR
imaging (DTI) in areas of white matter (WM) damage is generally associated with increase of …

Looking at my body. Similarities and differences between anorexia nervosa patients and controls in body image visual processing

…, E Bolognesi, A D'Argenio, A Ginestroni… - European …, 2013 - cambridge.org
BackgroundBody image distortion is a core symptom of eating disorders. Functional magnetic
resonance imaging (fMRI) studies on body image processing, described different patterns …

Whole-brain histogram and voxel-based analyses of diffusion tensor imaging in patients with leukoaraiosis: correlation with motor and cognitive impairment

…, S Foresti, A Pratesi, A Ginestroni… - American journal …, 2007 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Cerebral white matter changes, termed leukoaraiosis (LA),
appearing as areas of increased signal intensity in T2-weighted MR images, are common …

Brain white matter tracts degeneration in Friedreich ataxia. An in vivo MRI study using tract-based spatial statistics and voxel-based morphometry

R Della Nave, A Ginestroni, C Tessa, E Salvatore… - Neuroimage, 2008 - Elsevier
BACKGROUND AND PURPOSE:: Neuropathological examination in Friedreich ataxia (FRDA)
reveals neuronal loss in the gray matter (GM) nuclei and degeneration of the white matter …

Brain white matter damage in SCA1 and SCA2. An in vivo study using voxel-based morphometry, histogram analysis of mean diffusivity and tract-based spatial …

R Della Nave, A Ginestroni, C Tessa, E Salvatore… - Neuroimage, 2008 - Elsevier
BACKGROUND AND PURPOSE: Neurodegeneration in spinocerebellar ataxia type 1(SCA1)
and 2(SCA2) is associated with white matter(WM) damage. Voxel-Based Morphometry(…

White matter microstructural damage in small vessel disease is associated with Montreal cognitive assessment but not with mini mental state examination …

…, S Nannucci, F Pescini, R Valenti, A Ginestroni… - Stroke, 2015 - Am Heart Assoc
Background and Purpose— Montreal Cognitive Assessment (MoCA) has been proposed as
a screening tool in vascular cognitive impairment. Diffusion tensor imaging is sensitive to …

Brain structural damage in Friedreich's ataxia

R Della Nave, A Ginestroni, M Giannelli… - Journal of Neurology …, 2008 - jnnp.bmj.com
Objective: Neuropathological descriptions of the brain in Friedreich’s ataxia (FRDA) were
obtained before availability of the current molecular genetic tests for this disease. Voxel-based …

Brainstem neurodegeneration correlates with clinical dysfunction in SCA1 but not in SCA2. A quantitative volumetric, diffusion and proton spectroscopy MR study

L Guerrini, F Lolli, A Ginestroni, G Belli, RD Nave… - Brain, 2004 - academic.oup.com
Magnetic resonance (MR) techniques enable in vivo measurement of the atrophy of the
brainstem and cerebellum in spinocerebellar ataxia type 1 (SCA1) and 2 (SCA2) patients, which …

Assessment of brain white matter fiber bundle atrophy in patients with Friedreich ataxia

E Pagani, A Ginestroni, R Della Nave, F Agosta, F Salvi… - Radiology, 2010 - pubs.rsna.org
Purpose To investigate in vivo severity and topographic distribution of brain white matter (WM)
fiber bundle atrophy in patients with Friedreich ataxia, a condition characterized by an …