IL-17 is a potent proinflammatory cytokine produced by activated memory T cells. The large-scale
sequencing of the human and other vertebrate genomes has revealed the presence of …

Specific Ca 2+ homeostatic system appeared very early in the history of the cell, as a survival
system preventing Ca 2+ -mediated cell damage. This homeostatic system produced a …

IL-22, also termed IL-TIF, is a member of the IL-10 family of cytokines. Its principal source
appears to be memory CD4 T cells with a Th1 polarized phenotype. IL-22 induces its signals …

Familial hemophagocytic lymphohistiocytosis (FHL) is an autosomal recessive disease of
early childhood characterized by nonmalignant accumulation and multivisceral infiltration of …

Heterozygous germ-line mutations in the DNA mismatch repair genes lead to hereditary
nonpolyposis colorectal cancer. The disease susceptibility of individuals who constitutionally …

Red cell distribution width (RDW) was studied in adults carrying δ‐β thalassemia traits (δβ‐TT)
who were 20–40 years of age (n = 29), β thalassemia traits (β‐TT) with an age range of 18…

Recent observations indicate that, in several types of human cancer, only a phenotypic
subset of cancer cells within each tumor is capable of initiating tumor growth. This functional …

Vertebrates and invertebrates initiate a series of defence mechanisms following infection by
Gram-negative bacteria by sensing the presence of lipopolysaccharide (LPS), a major …

Physiological platelet synthesis is thought to require the humoral activities of meg-CSF and
thrombopoietin, which respectively promote proliferation and maturation of megakaryocytic …

Interleukin (IL)-17 is a pro-inflammatory cytokine that is produced by activated T cells.
Despite increasing evidence that high levels of IL-17 are associated with several chronic …