The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock
2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis and …

An epidemiological survey in the Northwest Greenland reported that the Greenlanders have
a lower frequency of acute myocardial infarction and diabetes mellitus. The very low …

Periostin is a matricellular protein as well as an extracellular matrix (ECM) protein belonging
to the fasciclin family. Periostin plays important roles as a matricellular protein in the setting …

Purpose Programmed death-1 (PD-1), a coinhibitory immune signal receptor expressed in T
cells, binds to PD-1 ligand and regulates antitumor immunity. Nivolumab is an anti–PD-1 …

Neurogenesis persists in the adult mammalian hippocampus. To identify and isolate
neuronal progenitor cells of the adult human hippocampus, we transfected ventricular zone-free …

Recent studies demonstrated the neuronogenic role of radial glial cells (RGCs) in the rodent.
To reveal the fate of radial glial processes, we intensively monitored divisions of RGCs in …

Although thousands of long noncoding RNAs (lncRNAs) are localized in the nucleus, only a
few dozen have been functionally characterized. Here we show that nuclear enriched …

Mature neocortical layers all derive from the cortical plate (CP), a transient zone in the
dorsal telencephalon into which young neurons are continuously delivered. To understand …

Retinoic acid inducible gene I (RIG-I)-like receptors (RLRs) function as cytoplasmic sensors
for viral RNA to initiate antiviral responses including type I interferon (IFN) production. It has …

To investigate the mechanism of I − transport stimulation by TSH, we studied the effects of
TSH on Na + /I − symporter (NIS) messenger RNA (mRNA) and protein levels in FRTL-5 cells …