The most fatal malignancy of the central nervous system (CNS) is glioblastoma. Brain cancer
is a ‘cold’ tumor because of fewer immunoregulatory cells and more immunosuppressive …

Although frequently discussed in terms of sex dimorphism, the neurobiology of sexual
orientation and identity is unknown. We report multimodal magnetic resonance imaging data, …

Both transgenderism and homosexuality are facets of human biology, believed to derive
from different sexual differentiation of the brain. The two phenomena are, however, …

Transgender individuals experience incongruence between their gender identity and birth-assigned
sex. The resulting gender dysphoria (GD), which some gender-incongruent …

Women with complete androgen insensitivity syndrome (CAIS) have a male (46,XY) karyotype
but no functional androgen receptors. Their condition, therefore, offers a unique model for …

Gender dysphoria (GD) is characterized by incongruence between onés gender assigned at
birth and the gender that one identifies with. The biological mechanisms of GD are unclear, …

Background Biomarkers of psychiatric treatment response remain elusive. Functional magnetic
resonance imaging (fMRI) has shown promise, but low reliability has limited the utility of …

Gender identity is a core aspect of self-identity and is usually congruent with birth-assigned
sex and own body sex-perception. The neuronal circuits underlying gender identity are …

MRI diffusion tensor imaging (DTI) studies of white matter integrity in behavioral variant
frontotemporal dementia have consistently shown involvement of frontal and temporal white …

The neurobiology of sexual orientation is frequently discussed in terms of cerebral sex
dimorphism (defining both functional and structural sex differences). Yet, the information about …