User profiles for A. Pikula
Aleksandra PikulaAssociate Professor of Medicine(Neurology) - University of Toronto Verified email at uhn.ca Cited by 4982 |
Cerebral collateral circulation in carotid artery disease
Carotid artery disease is common and increases the risk of stroke. However, there is wide
variability on the severity of clinical manifestations of carotid disease, ranging from …
variability on the severity of clinical manifestations of carotid disease, ranging from …
Stroke prevention: modifying risk factors
Risk factor modification remains as the principal aspect of care for stroke prevention.
Understanding of risk factors has advanced and several options are now available to treat …
Understanding of risk factors has advanced and several options are now available to treat …
Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial
Background Whether thrombectomy alone is equally as effective as intravenous alteplase
plus thrombectomy remains controversial. We aimed to determine whether thrombectomy …
plus thrombectomy remains controversial. We aimed to determine whether thrombectomy …
Red blood cell omega-3 fatty acid levels and markers of accelerated brain aging
Objective: Higher dietary intake and circulating levels of docosahexaenoic acid (DHA) and
eicosapentaenoic acid (EPA) have been related to a reduced risk for dementia, but the …
eicosapentaenoic acid (EPA) have been related to a reduced risk for dementia, but the …
Serum brain-derived neurotrophic factor and the risk for dementia: the Framingham Heart Study
Importance In animal studies, brain-derived neurotrophic factor (BDNF) has been shown to
impact neuronal survival and function and improve synaptic plasticity and long-term memory. …
impact neuronal survival and function and improve synaptic plasticity and long-term memory. …
Parental occurrence of stroke and risk of stroke in their children: the Framingham study
Background— Data relating parental history of stroke to stroke risk in offspring remain
surprisingly inconsistent, largely because of heterogeneity of study design and the absence of …
surprisingly inconsistent, largely because of heterogeneity of study design and the absence of …
Insulin-like growth factor-1 and risk of Alzheimer dementia and brain atrophy
…, TB Harris, TC Chen, X He, R Roubenoff, A Pikula… - Neurology, 2014 - AAN Enterprises
Objective: To relate serum insulin-like growth factor-1 (IGF-1) to risk of Alzheimer disease (AD)
dementia and to brain volumes in a dementia-free community sample spanning middle …
dementia and to brain volumes in a dementia-free community sample spanning middle …
Endovascular management of acute stroke in the elderly: a systematic review and meta-analysis
…, A Rabinstein, J Schaafsma, A Pikula… - American Journal …, 2018 - Am Soc Neuroradiology
Background: Acute ischemic stroke occurs more frequently, presents with more severe
symptoms, and has worse outcomes in elderly patients. The safety and efficacy of endovascular …
symptoms, and has worse outcomes in elderly patients. The safety and efficacy of endovascular …
Serum brain–derived neurotrophic factor and vascular endothelial growth factor levels are associated with risk of stroke and vascular brain injury: Framingham study
Background and Purpose— Brain-derived neurotrophic factor (BDNF), a major neurotrophin
and vascular endothelial growth factor (VEGF) have a documented role in neurogenesis, …
and vascular endothelial growth factor (VEGF) have a documented role in neurogenesis, …
Identification of senescence-associated genes from daylily petals
T Panavas, A Pikula, PD Reid, B Rubinstein… - Plant Molecular …, 1999 - Springer
The petals of daylily (Hemerocallis hybrid) have a genetically based program that leads to
senescence and cell death ca. 24 h after the flower opens. In order to determine the …
senescence and cell death ca. 24 h after the flower opens. In order to determine the …