An Essential Role of Alternative Splicing of c-myc Suppressor FUSE-Binding Protein–Interacting Repressor in Carcinogenesis

K Matsushita, T Tomonaga, H Shimada, A Shioya… - Cancer research, 2006 - AACR
Elevated expression of c-myc has been detected in a broad range of human cancers,
indicating a key role for this oncogene in tumor development. Recently, an interaction between …

Lewy body pathology involves the olfactory cells in Parkinson's disease and related disorders

Y Saito, A Shioya, T Sano, H Sumikura… - Movement …, 2016 - Wiley Online Library
Background The “dual‐hit” and propagation hypotheses of α‐synuclein suggests that the
olfactory cells of the olfactory epithelium are among the earliest sites of involvement in …

Strong HLA‐DR antigen expression on cancer cells relates to better prognosis of colorectal cancer patients: Possible involvement of c‐myc suppression by interferon …

…, T Tomonaga, H Hayashi, A Shioya… - Cancer …, 2006 - Wiley Online Library
Strong HLA‐DR antigen expression on cancer cells relates to better prognosis of colorectal
cancer patients, although the precise mechanism is controversial. From an immunological …

Clinical, biochemical and molecular investigation of adult-onset glutaric acidemia type II: characteristics in comparison with pediatric cases

…, T Tsunemi, H Mizusawa, H Takuma, A Shioya… - Brain and …, 2016 - Elsevier
Introduction An increasing number of adult patients have been diagnosed with fatty acid β-oxidation
disorders with the rising use of diagnostic technologies. In this study, clinical, …

Neurodegenerative changes in patients with clinical history of bipolar disorders

A Shioya, Y Saito, K Arima, Y Kakuta… - …, 2015 - Wiley Online Library
Neurodegeneration in bipolar disorder ( BPD ) is poorly understood. Therefore, the current
study was designed to assess the immunohistochemical changes in neurodegenerative …

Purification, characterization, and gene cloning of 46 kDa chitinase (Chi46) from Trichoderma reeseiPC-3-7 and its expression in Escherichia coli

M Ike, K Nagamatsu, A Shioya, M Nogawa… - Applied microbiology …, 2006 - Springer
We purified a chitinase (named Chi46), with a molecular mass of 46 kDa estimated by
sodium dodecyl sulfate−polyacrylamide gel electrophoresis, from the culture filtrate of …

[HTML][HTML] An extranodal histopathological analysis of idiopathic multicentric Castleman disease with and without TAFRO syndrome

N Kurose, K Mizutani, M Kumagai, A Shioya… - … -Research and Practice, 2019 - Elsevier
Thrombocytopenia, anasarca, fever, renal failure or reticulin fibrosis, and organomegaly (TAFRO)
syndrome, a poor prognostic clinical condition showing similar histopathological …

[HTML][HTML] In vivo synaptic activity-independent co-uptakes of amyloid β1–42 and Zn2+ into dentate granule cells in the normal brain

H Tamano, N Oneta, A Shioya, PA Adlard, AI Bush… - Scientific Reports, 2019 - nature.com
Neuronal amyloid β 1–42 (Aβ 1–42 ) accumulation is considered an upstream event in
Alzheimer’s disease pathogenesis. Here we report the mechanism on synaptic activity-…

[HTML][HTML] PRDX4 improved aging-related delayed wound healing in mice

…, X Guo, J Zheng, J Zhang, J Han, A Shioya… - Journal of Investigative …, 2021 - Elsevier
Aging-related delayed wound healing is an issue of concern worldwide. Oxidative stress is
involved in wound healing. Antioxidative enzymes have various roles in this process. PRDX4, …

[HTML][HTML] The impact of PRDX4 and the EGFR mutation status on cellular proliferation in lung adenocarcinoma

K Mizutani, X Guo, A Shioya, J Zhang… - … journal of medical …, 2019 - ncbi.nlm.nih.gov
Background: Oxidative stress plays key roles in the progression of lung adenocarcinoma.
Recently, we reported that peroxiredoxin 4 (PRDX4), an antioxidant enzyme, can be a …