Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis
H Lemjabbar-Alaoui, A van Zante, MS Singer, Q Xue… - Oncogene, 2010 - nature.com
Heparan sulfate (HS) proteoglycans (HSPGs) bind to multiple growth factors/morphogens
and regulate their signaling. 6-O-sulfation (6S) of glucosamine within HS chains is critical for …
and regulate their signaling. 6-O-sulfation (6S) of glucosamine within HS chains is critical for …
[PDF][PDF] Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes
CD8 + T cell responses are critical for anti-tumor immunity. While extensively profiled in the
tumor microenvironment, recent studies in mice identified responses in lymph nodes (LNs) …
tumor microenvironment, recent studies in mice identified responses in lymph nodes (LNs) …
The prognostic role of sex, race, and human papillomavirus in oropharyngeal and nonoropharyngeal head and neck squamous cell cancer
BACKGROUND Human papillomavirus (HPV) is a well‐established prognostic marker for
oropharyngeal squamous cell cancer (OPSCC). Because of the limited numbers of women …
oropharyngeal squamous cell cancer (OPSCC). Because of the limited numbers of women …
Increasing prevalence of human papillomavirus–positive oropharyngeal cancers among older adults
BACKGROUND The incidence of oropharyngeal squamous cell carcinoma (OPSCC) is
increasing among older adults. It is unknown whether these trends can be explained by human …
increasing among older adults. It is unknown whether these trends can be explained by human …
[HTML][HTML] Extracellular sulfatases, elements of the Wnt signaling pathway, positively regulate growth and tumorigenicity of human pancreatic cancer cells
R Nawroth, A van Zante, S Cervantes, M McManus… - PloS one, 2007 - journals.plos.org
Background Heparan sulfate proteoglycans (HSPGs) are control elements in Wnt signaling,
which bind extracellularly to Wnt ligands and regulate their ability to interact with signal …
which bind extracellularly to Wnt ligands and regulate their ability to interact with signal …
[HTML][HTML] Molecular diagnostics in human papillomavirus-related head and neck squamous cell carcinoma
KC Wai, MP Strohl, A van Zante, PK Ha - Cells, 2020 - mdpi.com
The incidence of human papillomavirus (HPV)-related head and neck squamous cell carcinoma
continues to increase. Accurate diagnosis of the HPV status of a tumor is vital, as HPV+ …
continues to increase. Accurate diagnosis of the HPV status of a tumor is vital, as HPV+ …
Differences in the prevalence of human papillomavirus (HPV) in head and neck squamous cell cancers by sex, race, anatomic tumor site, and HPV detection method
Importance Human papillomavirus (HPV) causes an increasing proportion of oropharyngeal
squamous cell carcinomas (OPSCCs), particularly in white men. The prevalence of HPV …
squamous cell carcinomas (OPSCCs), particularly in white men. The prevalence of HPV …
Lack of association of BRAF mutation with negative prognostic indicators in papillary thyroid carcinoma: the University of California, San Francisco, experience
…, A Bostrom, JP Grenert, A van Zante… - … –head & neck …, 2013 - jamanetwork.com
Importance Papillary thyroid carcinoma (PTC) is the most common endocrine neoplasm. B-type
raf kinase (BRAF) V600E mutation has been proposed as a negative prognostic …
raf kinase (BRAF) V600E mutation has been proposed as a negative prognostic …
[PDF][PDF] Sulfation of L-selectin ligands by an HEV-restricted sulfotransferase regulates lymphocyte homing to lymph nodes
S Hemmerich, A Bistrup, MS Singer, A van Zante… - Immunity, 2001 - cell.com
Lymphocytes home to lymph nodes, using L-selectin to bind specific ligands on high
endothelial venules (HEV). In vitro studies implicate GlcNAc-6-sulfate as an essential …
endothelial venules (HEV). In vitro studies implicate GlcNAc-6-sulfate as an essential …
[HTML][HTML] Vascular endothelial junction-associated molecule, a novel member of the immunoglobulin superfamily, is localized to intercellular boundaries of endothelial …
D Palmeri, A van Zante, CC Huang… - Journal of Biological …, 2000 - ASBMB
During the process of lymphocyte homing to secondary lymphoid organs, such as lymph
nodes and tonsils, lymphocytes interact with and cross a specialized microvasculature, known …
nodes and tonsils, lymphocytes interact with and cross a specialized microvasculature, known …