Traumatic brain injury damages white matter pathways that connect brain regions, disrupting
transmission of electrochemical signals and causing cognitive and emotional dysfunction. …

BACKGROUND AND PURPOSE: Quantitative assessment of clinical and pathologic
consequences of white matter abnormalities in multiple sclerosis is critical in understanding the …

Chronic motor impairments are a leading cause of disability after stroke. Previous studies have
predicted motor outcomes based on the degree of damage to predefined structures in the …

Computational models provide a useful tool for experimentalists in understanding the
processes occurring in a biological system that may otherwise be impossible toobserve directly. …

Background Multiple Sclerosis (MS), a neurodegenerative and neuroinflammatory disease,
causing lesions that disrupt the brain’s anatomical and physiological connectivity networks, …

Background Multiple Sclerosis (MS) is a disease characterized by inflammation, demyelination,
and/or axonal loss that disrupts white matter pathways that constitute the brain’s …

White matter structural connections are likely to support flow of functional activation or
functional connectivity. While the relationship between structural and functional connectivity …

Motor recovery following ischemic stroke is contingent on the ability of surviving brain
networks to compensate for damaged tissue. In rodent models, sensory and motor cortical …

… Susan Gauthier and Amy Kuceyeski contributed equally to this work. … Safi, Thanh Nguyen,
Susan Gauthier, Amy Kuceyeski, The sequence of regional structural disconnectivity due to …

The development of accurate prognoses in multiple sclerosis is difficult, as the disease is
characterized by heterogeneous patterns of brain abnormalities that relate in an unclear way to …