User profiles for A.F. Saad

AF Saad

Professor of Experimental Nuclear Physics
Verified email at zu.edu.eg
Cited by 605

[HTML][HTML] Microenvironment and pathogenesis of epithelial ovarian cancer

AF Saad, W Hu, AK Sood - Hormones and cancer, 2010 - Springer
Multiple genetic alterations play a role in the pathogenesis of ovarian cancer. Although many
key proteins and pathways involved in ovarian carcinogenesis and metastasis have been …

[HTML][HTML] Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids

…, H Fu, R Morizane, V Agrawal, AF Saad… - Nature …, 2015 - nature.com
Human-pluripotent-stem-cell-derived kidney cells (hPSC-KCs) have important potential for
disease modelling and regeneration. Whether the hPSC-KCs can reconstitute tissue-specific …

[HTML][HTML] Imaging of atypical and complicated posterior reversible encephalopathy syndrome

AF Saad, R Chaudhari, M Wintermark - Frontiers in neurology, 2019 - frontiersin.org
Posterior reversible encephalopathy syndrome (PRES) is a condition clinically characterized
by headache, altered mental status, seizures, and visual loss and may be associated with …

Timing of birth and adverse pregnancy outcomes in cases of prenatally diagnosed vasa previa: a systematic review and meta-analysis

…, H Erfani, SA Shainker, AF Saad… - American journal of …, 2022 - Elsevier
Objective The ideal time for birth in pregnancies diagnosed with vasa previa remains unclear.
We conducted a systematic review aiming to identify the gestational age at delivery that …

Corticosteroids in the management of pregnant patients with coronavirus disease (COVID-19)

AF Saad, L Chappell, GR Saade… - Obstetrics & …, 2020 - journals.lww.com
Recent evidence supports the use of an early, short course of glucocorticoids in patients
with COVID-19 who require mechanical ventilation or oxygen support. As the number of …

[HTML][HTML] OxLDL immune complexes activate complement and induce cytokine production by MonoMac 6 cells and human macrophages

AF Saad, G Virella, C Chassereau, RJ Boackle… - Journal of lipid …, 2006 - ASBMB
Oxidized low density lipoprotein (OxLDL) is immunogenic and induces autoimmune responses
in humans. OxLDL antibodies are predominantly of the proinflammatory IgG1 and IgG3 …

High-fructose diet in pregnancy leads to fetal programming of hypertension, insulin resistance, and obesity in adult offspring

AF Saad, J Dickerson, TB Kechichian, H Yin… - American Journal of …, 2016 - Elsevier
Background Consumption of fructose-rich diets in the United States is on the rise and
thought to be associated with obesity and cardiometabolic diseases. Objective We sought to …

The functional effects of acid ceramidase over-expression in prostate cancer progression and resistance to chemotherapy

AF Saad, WD Meacham, A Bai, V Anelli… - Cancer biology & …, 2007 - Taylor & Francis
Among the many processes regulating cell death, ceramide signaling is a vital component.
We previously determined that acid ceramidase (AC) is upregulated in 60% of primary …

Effects of pravastatin on angiogenic and placental hypoxic imbalance in a mouse model of preeclampsia

AF Saad, T Kechichian, H Yin, E Sbrana… - Reproductive …, 2014 - journals.sagepub.com
In order to determine the effects of pravastatin (Pra) on angiogenic and placental hypoxic
imbalance in a model of preeclampsia induced by overexpression of soluble fms-like tyrosine …

Association of the Delta (B. 1.617. 2) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with pregnancy outcomes

…, LD Pacheco, GR Saade, AF Saad - Obstetrics & …, 2021 - journals.lww.com
METHODS We conducted a retrospective cohort study at a single academic center. The
study was approved by University of Texas Medical Branch at Galveston Institutional Review …