DHCR7: A vital enzyme switch between cholesterol and vitamin D production
The conversion of 7-dehydrocholesterol to cholesterol, the final step of cholesterol synthesis
in the Kandutsch-Russell pathway, is catalyzed by the enzyme 7-dehydrocholesterol …
in the Kandutsch-Russell pathway, is catalyzed by the enzyme 7-dehydrocholesterol …
Performance and emission evaluation of dual fuel CI engine using preheated biogas-air mixture
In this work, the effect of the preheated biogas-air mixture in a biogas-diesel dual fuel CI engine
was evaluated. The intake biogas-air mixture was heated by engine exhaust gas using a …
was evaluated. The intake biogas-air mixture was heated by engine exhaust gas using a …
[PDF][PDF] CRISPR interference-based platform for multimodal genetic screens in human iPSC-derived neurons
…, MT Laurie, JY Hong, D Nathaniel, AV Prabhu… - Neuron, 2019 - cell.com
CRISPR/Cas9-based functional genomics have transformed our ability to elucidate mammalian
cell biology. However, most previous CRISPR-based screens were conducted in cancer …
cell biology. However, most previous CRISPR-based screens were conducted in cancer …
Incidence of and risk factors for skin cancer in organ transplant recipients in the United States
…, J Oulton, PH Patel, VA Patel, AV Prabhu… - JAMA …, 2017 - jamanetwork.com
Importance Skin cancer is the most common malignancy occurring after organ transplantation.
Although previous research has reported an increased risk of skin cancer in solid organ …
Although previous research has reported an increased risk of skin cancer in solid organ …
Mobile health applications for atrial fibrillation: a readability and quality assessment
…, T Crihalmeanu, F Thelmo, AV Prabhu… - International journal of …, 2019 - Elsevier
Background Mobile health applications may improve patient education and self-care for a
complex condition such as atrial fibrillation (AF). Little is known about the accessibility of …
complex condition such as atrial fibrillation (AF). Little is known about the accessibility of …
[HTML][HTML] Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features
…, M Oates, D Cavalieri, J Gibson, AV Prabhu… - Nature …, 2022 - nature.com
The value of genome-wide over targeted driver analyses for predicting clinical outcomes of
cancer patients is debated. Here, we report the whole-genome sequencing of 485 chronic …
cancer patients is debated. Here, we report the whole-genome sequencing of 485 chronic …
[HTML][HTML] Cholesterol-mediated degradation of 7-dehydrocholesterol reductase switches the balance from cholesterol to vitamin D synthesis
Cholesterol is detrimental to human health in excess but is also essential for normal
embryogenesis. Hence, enzymes involved in its synthesis possess many layers of regulation to …
embryogenesis. Hence, enzymes involved in its synthesis possess many layers of regulation to …
Early oral tongue squamous cell carcinoma: sampling of margins from tumor bed and worse local control
Importance Positive margins are associated with poor prognosis among patients with oral
tongue squamous cell carcinoma (SCC). However, wide variation exists in the margin …
tongue squamous cell carcinoma (SCC). However, wide variation exists in the margin …
WITHDRAWN: Machine learning models for covid-19 future forecasting
RK Mojjada, A Yadav, AV Prabhu, Y Natarajan - 2020 - Elsevier
Withdrawal Notice WITHDRAWN: Machine learning models for covid-19 future
forecastingRamesh Kumar Mojjada a, ⇑, Arvind Yadav a, AV Prabhu b, Yuvaraj Natarajan ca …
forecastingRamesh Kumar Mojjada a, ⇑, Arvind Yadav a, AV Prabhu b, Yuvaraj Natarajan ca …
New insights into cellular cholesterol acquisition: promoter analysis of human HMGCR and SQLE, two key control enzymes in cholesterol synthesis
Background The two control points of cholesterol synthesis, 3-hydroxy-3-methylglutaryl-coenzyme
A reductase (HMGCR) and squalene monooxygenase (SQLE) are known targets of …
A reductase (HMGCR) and squalene monooxygenase (SQLE) are known targets of …