Nasopharyngeal carcinoma of the undifferentiated subtype is endemic to southern China,
and patient prognosis has improved significantly over the past three decades because of …

The Rho guanosine triphosphatases (GTPases) Rac1 and Rac2 are critical signaling
regulators in mammalian cells. The deletion of both Rac1 and Rac2 murine alleles leads to a …

Central retinal artery occlusion (CRAO) is an ophthalmic emergency and the ocular
analogue of cerebral stroke. Best evidence reflects that over three-quarters of patients suffer …

… Anna W Lee … Anna W Lee … Dr Budac, Dr Lee, and Ms Bisulco are employed by
Lundbeck Laboratories. The remaining authors report no conflicts of interest. …

The kynurenine pathway (KP) metabolizes the essential amino acid tryptophan and generates
a number of neuroactive metabolites collectively called the kynurenines. Segregated into …

We live in the golden age of distributed computing. Public cloud platforms now offer virtually
unlimited compute and storage resources on demand. At the same time, the Software-as-a-…

The molecular events that regulate engraftment and mobilization of hematopoietic stem cells
and progenitors (HSC/Ps) are still incompletely defined 1 , 2 . We have examined the role of …

Purpose Target delineation in nasopharyngeal carcinoma (NPC) often proves challenging
because of the notoriously narrow therapeutic margin. High doses are needed to achieve …

Dendritic cells (DCs) can induce tumor- or pathogen-specific T cell responses in humans. We
comprehensively compared the clinically available DC maturation stimuli for their ability to …

The Rosario Cu-Mo-Ag deposit is located in the Collahuasi district of northern Chile. It
comprises high-grade Cu-Ag-(Au) epithermal veins, superimposed on the core of a porphyry Cu-…