Whole-body hypothermia for neonates with hypoxic–ischemic encephalopathy

S Shankaran, AR Laptook… - … England Journal of …, 2005 - Mass Medical Soc
Background Hypothermia is protective against brain injury after asphyxiation in animal
models. However, the safety and effectiveness of hypothermia in term infants with …

Neonatal outcomes of extremely preterm infants from the NICHD Neonatal Research Network

…, NI Hansen, EF Bell, S Shankaran, AR Laptook… - …, 2010 - publications.aap.org
OBJECTIVE: This report presents data from the Eunice Kennedy Shriver National Institute of
Child Health and Human Development Neonatal Research Network on care of and …

[HTML][HTML] Therapeutic hypothermia translates from ancient history in to practice

AJ Gunn, AR Laptook, NJ Robertson, JD Barks… - Pediatric …, 2017 - nature.com
Acute postasphyxial encephalopathy around the time of birth remains a major cause of death
and disability. The possibility that hypothermia may be able to prevent or lessen asphyxial …

Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network

…, SB Korones, S Shankaran, AR Laptook… - …, 2002 - publications.aap.org
Objective. Late-onset sepsis (occurring after 3 days of age) is an important problem in very
low birth weight (VLBW) infants. To determine the current incidence of late-onset sepsis, risk …

Trends in care practices, morbidity, and mortality of extremely preterm neonates, 1993-2012

…, MC Walsh, WA Carlo, S Shankaran, AR Laptook… - Jama, 2015 - jamanetwork.com
Importance Extremely preterm infants contribute disproportionately to neonatal morbidity and
mortality. Objective To review 20-year trends in maternal/neonatal care, complications, and …

Trends in neonatal morbidity and mortality for very low birthweight infants

…, EF Donovan, SB Korones, AR Laptook… - American journal of …, 2007 - Elsevier
OBJECTIVE: To document the mortality and morbidity of infants weighing 501-1500 g at birth
according to gestational age, birthweight, and sex. STUDY DESIGN: Prospective collection …

Early Onset Neonatal Sepsis: The Burden of Group B Streptococcal and E. coli Disease Continues

…, EF Bell, MC Walsh, K Schibler, AR Laptook… - …, 2011 - publications.aap.org
BACKGROUND: Guidelines for prevention of group B streptococcal (GBS) infection have
successfully reduced early onset (EO) GBS disease. Study results suggest that Escherichia coli …

[HTML][HTML] Changes in pathogens causing early-onset sepsis in very-low-birth-weight infants

…, SB Korones, S Shankaran, AR Laptook… - … England Journal of …, 2002 - Mass Medical Soc
Background It is uncertain whether the rates and causes of early-onset sepsis (that occurring
within 72 hours after birth) among very-low-birth-weight infants have changed in recent …

Birth asphyxia and hypoxic-ischemic brain injury in the preterm infant

AR Laptook - Clinics in perinatology, 2016 - perinatology.theclinics.com
Identification of infants! 36 weeks’ gestation with perinatal hypoxia-ischemia or asphyxia has
allowed investigation of potential neuroprotective treatments. Therapeutic hypothermia is …

Mortality, in-hospital morbidity, care practices, and 2-year outcomes for extremely preterm infants in the US, 2013-2018

…, RM Patel, SL Merhar, PJ Sánchez, AR Laptook… - Jama, 2022 - jamanetwork.com
Importance Despite improvement during recent decades, extremely preterm infants continue
to contribute disproportionately to neonatal mortality and childhood morbidity. Objective To …