The relationship of relapses to long-term disability in multiple sclerosis is uncertain.
Relapse reduction is a common therapeutic target but clinical trials have shown dissociation …

This Review summarizes the natural history studies on multiple sclerosis (MS) that have
evaluated prognostic factors. Reassessment of prognostic factors is warranted, as our ability to …

A case of multiple sclerosis presenting during anti–tumor necrosis factor treatment for
rheumatoid arthritis is discussed. This association has been reported in the nonradiological …

Multiple sclerosis (MS) is a common inflammatory disease of the central nervous system (CNS),
the clinical course of which varies considerably between patients. Genetic complexity …

Purpose To evaluate techniques for anatomical and physiological imaging of the intracranial
optic nerve (ON), optic chiasm (OC), and optic tract (OT) at 3T with the aim of visualizing …

Multiple sclerosis (MS) is a common inflammatory disease of the central nervous system
unsurpassed for its variability in disease outcome. As little is conclusively known about MS …

Multiple sclerosis (MS) is a common inflammatory disease of the central nervous system
unsurpassed for its variability in disease outcome. It has been observed that axonal loss in MS …

Multiple sclerosis (MS) is a common inflammatory disease of the central nervous system
unsurpassed for its variability in disease outcome. Given a possible role for dysregulation of iron …

Multiple sclerosis (MS) is a common inflammatory disease of the central nervous system
unsurpassed for its variability in disease outcome. Apolipoprotein E (APOE) is involved in …

The rhesus macaque (Macaca mulatta) is an abundant primate species that diverged from
the ancestors of Homo sapiens about 25 million years ago. Because they are genetically and …