Tissue engineering: from biology to biological substitutes

RM Nerem, A Sambanis - Tissue engineering, 1995 - liebertpub.com
Tissue engineering is an emerging multidisciplinary and interdisciplinary field involving the
development of bioartificial implants and/or the fostering of tissue remodeling with the …

A biological hybrid model for collagen-based tissue engineered vascular constructs

JD Berglund, MM Mohseni, RM Nerem, A Sambanis - Biomaterials, 2003 - Elsevier
Various approaches to tissue engineering a small diameter blood vessel have historically
relied upon extended culturing periods and/or synthetic materials to create mechanical …

The role of the CaCl2–guluronic acid interaction on alginate encapsulated βTC3 cells

NE Simpson, CL Stabler, CP Simpson, A Sambanis… - Biomaterials, 2004 - Elsevier
Previously we demonstrated that alginate composition has a significant effect on the growth
of encapsulated βTC3 cells and consequently on the overall metabolic and secretory …

Effect of oxygen tension and alginate encapsulation on restoration of the differentiated phenotype of passaged chondrocytes

CL Murphy, A Sambanis - Tissue engineering, 2001 - liebertpub.com
The implantation of laboratory-grown tissue offers a valuable alternative approach to the
treatment of cartilage defects. Procuring sufficient cell numbers for such tissue-engineered …

Cytotoxicity effects of cryoprotectants as single-component and cocktail vitrification solutions

A Lawson, H Ahmad, A Sambanis - Cryobiology, 2011 - Elsevier
Cryoprotectant (CPA) cytotoxicity constitutes a challenge in developing cryopreservation
protocols, specifically in vitrification where high CPA concentrations are necessary to achieve …

Incorporation of intact elastin scaffolds in tissue-engineered collagen-based vascular grafts

JD Berglund, RM Nerem, A Sambanis - Tissue engineering, 2004 - liebertpub.com
Although collagen-based tissue-engineered blood vessels (TEBVs) have many interesting
properties and have been utilized to study aspects of vascular biology, these constructs are …

Tissue engineering of a bioartificial pancreas: modeling the cell environment and device function

E Tziampazis, A Sambanis - Biotechnology progress, 1995 - Wiley Online Library
Cell‐based implantable artificial tissues are most promising for the long‐term treatment of
endocrine diseases, such as diabetes. One type of a bioartificial pancreas device consists of …

Microencapsulated adult porcine islets transplanted intraperitoneally in streptozotocin‐diabetic non‐human primates

…, P Thompson, IR Badell, A Sambanis… - …, 2018 - Wiley Online Library
Background Xenogeneic donors would provide an unlimited source of islets for the
treatment of type 1 diabetes (T1D). The goal of this study was to assess the function of …

Alginate microencapsulation of human mesenchymal stem cells as a strategy to enhance paracrine‐mediated vascular recovery after hindlimb ischaemia

…, CA Flores, D Weiss, A Sambanis… - Journal of tissue …, 2016 - Wiley Online Library
Stem cell‐based therapies hold great promise as a clinically viable approach for vascular
regeneration. Preclinical studies have been very encouraging and early clinical trials have …

Mathematical modeling of cryoprotectant addition and removal for the cryopreservation of engineered or natural tissues

A Lawson, IN Mukherjee, A Sambanis - Cryobiology, 2012 - Elsevier
Long-term storage of natural tissues or tissue-engineered constructs is critical to allow off-the-shelf
availability. Vitrification is a method of cryopreservation that eliminates ice formation, …