Object While the use of endoscopic approaches has become increasingly accepted in the
resection of pituitary adenomas, limited evidence exists regarding the success of this …

Objective To analyze the actual risk for patients with a patent foramen ovale (PFO) to
experience a clinically relevant venous air embolism (VAE) during surgery performed in the …

… (B) Intimal hyperplasia in the middle cerebral artery from an autopsy of a 69-year-old case.
Intimal hyperplasia (red arrowhead), atrophic media (red arrow) and winding internal elastic …

… b Coronal reconstruction of the same patient depicting blood vessel (white arrow) and REZ
(yellow arrow). c Transversal 3D-FIESTA sequence (heavily T2-weighted sequence, equal to …

Saccular intracranial aneurysms are balloon-like dilations of the intracranial arterial wall;
their hemorrhage commonly results in severe neurologic impairment and death. We report a …

Gliomas represent approximately 30% of all central nervous system tumors and 80% of
malignant brain tumors 1 . To understand the molecular mechanisms underlying the malignant …

… (b) Alignment of the protein sequences of the large Pol II subunit for seven species shows
the dock domain, including the two residues altered by recurrent meningioma mutations, to be …

… (b) Atypical versus benign meningiomas harbour similar number of damaging somatic
mutations (atypical n=10, benign n=65). The lines above the bars indicate statistical analysis (…

The pathogenesis of intracranial aneurysm (IA) formation and rupture is complex, with
significant contribution from genetic factors. We previously reported genome-wide association …

Object Several studies have revealed that the gross-total resection (GTR) of malignant brain
tumors has a significant influence on patient survival. Frequently, however, GTR cannot be …