Interest is growing in the role of infectious agents in the pathogenesis of dementia, but current
evidence is limited. We conducted a systematic review and meta-analysis to investigate …

Syphilis is a resurgent sexually transmitted infection in the UK that is disproportionately
diagnosed in patients living with HIV, particularly in men who have sex with men. Syphilis …

… Basil Ridha and colleagues' study 1 in this issue is an important addition to the research
of imaging in Alzheimer's disease. The study was done by a group that has pioneered the …

A significant minority of Alzheimer's disease patients present with posterior cortical atrophy (PCA).
PCA is characterized by visuospatial and visuoperceptual deficits, and relatively …

Background: Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy
(PLOSL), or Nasu-Hakola disease, is a presenile dementia associated with loss of myelin…

Background Both cognitive tests and MRI-based measures have been suggested as outcomes
in trials assessing disease-modifying therapies in Alzheimer's disease (AD). Objective To …

Background Liraglutide is a glucagon-like peptide-1 (GLP-1) analogue currently approved
for type 2 diabetes and obesity. Preclinical evidence in transgenic models of Alzheimer’s …

Posterior cortical atrophy is a clinico-radiological syndrome characterized by progressive
decline in visual processing and atrophy of posterior brain regions. With the majority of cases …

Three patients with probable dementia with Lewy bodies (DLB) experienced worsening
delusions and visual hallucinations as a result of memantine therapy. Significant resolution …

Background Type 2 diabetes is a risk factor for Alzheimer’s disease (AD), and AD brain
shows impaired insulin signalling. The role of peripheral insulin resistance on AD …