Autoimmune encephalitis is a relatively new category of immune-mediated disease
involving the central nervous system that demonstrates a widely variable spectrum of clinical …

Purpose To conduct a systematic review of the literature to assess outcomes data on
complications associated with implant-based breast reconstruction performed before or after chest …

Protein–ligand structures are the core data required for structure-based drug design (SBDD).
Understanding the error present in this data is essential to the successful development of …

We implement a strategy for aligning two protein–protein interaction networks that combines
interaction topology and protein sequence similarity to identify conserved interaction …

PathBLAST is a network alignment and search tool for comparing protein interaction networks
across species to identify protein pathways and complexes that have been conserved by …

Mounting evidence shows that many protein complexes are conserved in evolution. Here we
use conservation to find complexes that are common to yeast S. Cerevisiae and bacteria H. …

Osteogenesis imperfecta (OI) is a genetic disorder of connective tissue characterized by
bone fragility and alteration in synthesis and posttranslational modification of type I collagen. …

Most patients with the pediatric neurodegenerative disease spinal muscular atrophy have a
homozygous deletion of the survival motor neuron 1 (SMN1) gene, but retain one or more …

We present a new approach to structure-based drug design (POSIT) rigorously built on the
simple concept that pose prediction is intimately coupled to the quality and availability of …

Purpose The specific aim of this study was to conduct a systematic review of the literature to
assess outcomes data on complications and aesthetic results associated with autologous …