Objective Treatment response assessment in high-grade gliomas uses contrast enhanced
T1-weighted MRI, but is unreliable. Novel advanced MRI techniques have been studied, but …

Treatment evaluation of patients with glioblastomas is important to aid in clinical decisions.
Conventional MRI with contrast is currently the standard method, but unable to differentiate …

… This work is supported by the University of Groningen (a Mandema stipendium to Anouk
van der Hoorn and a Junior Scientific Masterclass grant to Bart van Dijken). No other potential …

Background and purpose Glioblastoma exhibits profound intratumoral heterogeneity in
perfusion. Particularly, low perfusion may induce treatment resistance. Thus, imaging …

Isocitrate dehydrogenase (IDH) mutation status is an important biomarker in the glioma-defining
subtype and corresponding prognosis. This study proposes a straightforward method for …

Objectives: Radiation-induced changes (RIC) secondary to focal radiotherapy can imitate
tumour progression in brain metastases and make follow-up clinical decision making …

Background Radiotherapy (RT) and chemotherapy are components of standard multi-modality
treatment of high grade gliomas (HGG) aimed at achieving local tumor control. Treatment …

Glioblastoma is highly heterogeneous in microstructure and vasculature, creating various
tumor microenvironments among patients, which may lead to different phenotypes. The …

Purpose 11 C-Methionine ( 11 C-MET) PET prognostication of isocitrate dehydrogenase (IDH)
wild type glioblastomas is inadequate as conventional parameters such as standardized …

Simple Summary Glioblastomas are brain tumors with a poor prognosis, and early tumor
progression occurs often. Therefore, patients are closely monitored with regular MRI scans, …