The 2015 Magnetic Resonance Imaging in Multiple Sclerosis and 2016 Consortium of Multiple
Sclerosis Centres guidelines on the use of MRI in diagnosis and monitoring of multiple …

In patients presenting with a clinically isolated syndrome, MRI can support and substitute
clinical information in the diagnosis of multiple sclerosis by showing disease dissemination in …

The aging process is characterized by the chronic inflammatory status called “inflammaging”,
which shares major molecular and cellular features with the metabolism-induced …

Objective This study was undertaken to assess the impact of immunosuppressive and
immunomodulatory therapies on the severity of coronavirus disease 2019 (COVID‐19) in people …

Background: Spasticity is a disabling complication of multiple sclerosis, affecting many
patients with the condition. We report the first Phase 3 placebo‐controlled study of an oral …

Background Reliable prognostic factors are lacking for multiple sclerosis (MS). Gadolinium
enhancement in magnetic resonance imaging (MRI) of the brain detects with high sensitivity …

In a multicenter cross-sectional study, the authors assessed pain in patients with multiple
sclerosis (MS) using a symptom-oriented approach. Out of 2,077 questionnaires, we used …

Objective Gray matter (GM) atrophy occurs in all multiple sclerosis (MS) phenotypes. We
investigated whether there is a spatiotemporal pattern of GM atrophy that is associated with …

We designed a randomized, placebo-controlled, multicentre trial involving 51 relapsing-remitting
multiple sclerosis patients to determine the clinical efficacy of mitoxantrone treatment …

See Stankoff and Louapre (doi: 10.1093/brain/awy114 ) for a scientific commentary on this
article. Grey matter atrophy is present from the earliest stages of multiple sclerosis, but its …