User profiles for C Lee

Charlie Lees

- Verified email at ed.ac.uk - Cited by 31404

Christopher Lee

- Verified email at bc.edu - Cited by 17175

Chang Lee

- Verified email at llnl.gov - Cited by 9130

A gene map of the human genome

…, C East, C Edwards, JB Fan, N Fang, C Fizames… - Science, 1996 - science.org
The human genome is thought to harbor 50,000 to 100,000 genes, of which about half have
been sampled to date in the form of expressed sequence tags. An international consortium …

[HTML][HTML] Analyses of pig genomes provide insight into porcine demography and evolution

…, JH Kim, KW Kim, TH Kim, G Larson, K Lee, KT Lee… - Nature, 2012 - nature.com
For 10,000 years pigs and humans have shared a close and complex relationship. From
domestication to modern breeding practices, humans have shaped the genomes of domestic …

[HTML][HTML] The zebrafish reference genome sequence and its relationship to the human genome

…, B Plumb, J Davis, C Clee, K Oliver, R Clark, C Riddle… - Nature, 2013 - nature.com
Zebrafish have become a popular organism for the study of vertebrate gene function 1 , 2 .
The virtually transparent embryos of this species, and the ability to accelerate genetic studies …

2022 AHA/ACC/HFSA guideline for the management of heart failure: a report of the American College of Cardiology/American Heart Association Joint Committee on …

…, P Khazanie, MM Kittleson, CS Lee… - Journal of the American …, 2022 - jacc.org
… ) may become asymptomatic with treatment (NYHA class I), that patient will still be categorized
as stage C HF. Patients with stage C HF can be classified according to the trajectory of …

Designing dendrimers for biological applications

CC Lee, JA MacKay, JMJ Fréchet, FC Szoka - Nature biotechnology, 2005 - nature.com
Dendrimers are branched, synthetic polymers with layered architectures that show promise
in several biomedical applications. By regulating dendrimer synthesis, it is possible to …

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

…, C Gieger, J Glas, T Haritunians, A Hart, C Hawkey… - Nature, 2012 - nature.com
Crohn’s disease and ulcerative colitis, the two common forms of inflammatory bowel disease
(IBD), affect over 2.5 million people of European ancestry, with rising prevalence in other …

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

…, T Ahmad, CW Lees, T Balschun, J Lee… - Nature …, 2010 - nature.com
We undertook a meta-analysis of six Crohn's disease genome-wide association studies (GWAS)
comprising 6,333 affected individuals (cases) and 15,056 controls and followed up the …

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

…, CW Lees, A Franke, M D'Amato, KD Taylor, JC Lee… - Nature …, 2011 - nature.com
Genome-wide association studies and candidate gene studies in ulcerative colitis have
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis genome-…

Evidence for an Excess of Decays

…, C Patrignani, E Robutti, B Bhuyan, V Prasad, CL Lee… - Physical review …, 2012 - APS
Based on the full BABAR data sample, we report improved measurements of the ratios R (D
(*))= B (B→ D (*) τ− ν τ)/B (B→ D (*) ℓ ℓ− ν ℓ), where ℓ is either e or μ. These ratios are …

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

…, M Parkes, CW Lees, H Uhlig, C Hawkey… - Nature …, 2017 - nature.com
Genetic association studies have identified 215 risk loci for inflammatory bowel disease 1 ,
2 , 3 , 4 , 5 , 6 , 7 , 8 , thereby uncovering fundamental aspects of its molecular biology. We …