… During the past decade, considerable advances have been made in our understanding of
the pathophysiology of diarrhea and colitis caused by C. difficile infection, and a wide variety …

Because of mutations in this opportunistic pathogen, infections with C. difficile have become
both more prevalent and more virulent. This article summarizes recent changes in the …

Clostridium difficile infection is increasing in incidence, severity, and mortality. Treatment
options are limited and appear to be losing efficacy. Recurrent disease is especially challenging…

Although it is being successfully implemented for exploration of the genome, discovery
science has eluded the functional neuroimaging community. The core challenge remains the …

The peroxisome proliferator-activated receptor-γ (PPAR-γ) is a member of the nuclear receptor
superfamily of ligand-dependent transcription factors that is predominantly expressed in …

The National Center for Biotechnology Information (NCBI) produces a variety of online
information resources for biology, including the GenBank® nucleic acid sequence database and …

Triptolide (TP), a traditional Chinese medicine, has been reported to be effective in the
treatment of autoimmune diseases and exerting antineoplastic activity in several human tumor …

… C. difficile remains the most important cause of healthcareassociated diarrhea and is
increasingly important as a community pathogen. A more virulent strain of C. difficile has been …

Large language models (LLMs) have demonstrated impressive capabilities, but the bar for
clinical applications is high. Attempts to assess the clinical knowledge of models typically rely …

Background The scarcity of early biomarkers for acute renal failure has hindered our ability
to launch preventive and therapeutic measures for this disorder in a timely manner. We …