Background Cutis tricolor is a skin abnormality consisting in a combination of congenital
hyper-and hypopigmented skin lesions (in the form of paired macules, patches or streaks) in …

Background Mixed vascular nevus (or nevus vascularis mixtus) represents an admixture of
cutaneous vascular malformations of the telangiectatic type and angiospastic spots of nevus …

… 3 Schepis C, Barone C, Siragusa M, Romano C: Prevalence of atopic dermatitis in patients
with Down syndrome: A clinical survey. J Am Acad Dermatol 1997;36:1019–1021. 4 Polenghi …

PTEN gene is considered one of the most mutated tumor suppressor genes in human
cancer, and it’s likely to become the first one in the near future. Since 1997, its involvement in …

… In order to quantify the percentage of mosaicism in the c.808C > T (p.Gln270*) mutation,
we analyzed the sequencing-electropherogram of capillary electrophoresis performed on ABI …

… Fischer J, Blanchet-Bardon C, Prud’homme JF, et al.: Mapping of Papillon-Lefèvre syndrome
to the chromosome 11q 14 region. Eur J Hum Genet 5… Schepis reports no conflict of interest. …

Eruptive syringomas are uncommon in the general population. We describe here an 18-year-old
female, affected by Down’s syndrome, who presented with an abrupt eruption of small …

Autosomal recessive congenital ichthyoses (ARCI) are characterized by generalized skin
scaling, hyperkeratosis, erythroderma, and disabling features affecting the skin (palmoplantar …

Background It is well known that nails can be involved in some diseases of the central
nervous system; however, no systematic study has been carried out in order to evaluate the …

Macular or friction amyloidosis is a cutaneous entity characterized by a brownish pigmentation
distributed on the skin over bony regions of the trunk and limbs after the use, for many …