User profiles for C.-C. Lai

Chih-Chin Lai

National University of Kaohsiung
Verified email at nuk.edu.tw
Cited by 2609

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges

CC Lai, TP Shih, WC Ko, HJ Tang, PR Hsueh - International journal of …, 2020 - Elsevier
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; previously
provisionally named 2019 novel coronavirus or 2019-nCoV) disease (COVID-19) in …

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

EYHP Lee, CY Chang, N Hu, YCJ Wang, CC Lai… - Nature, 1992 - nature.com
The retinoblastoma gene, a prototypic tumour-suppressor gene, encodes a nuclear phosphoprotein
(Rb). To understand better the role of Rb in development and in tumorigenesis, mice …

[HTML][HTML] Asymptomatic carrier state, acute respiratory disease, and pneumonia due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): Facts and …

CC Lai, YH Liu, CY Wang, YH Wang, SC Hsueh… - Journal of Microbiology …, 2020 - Elsevier
Since the emergence of coronavirus disease 2019 (COVID-19) (formerly known as the 2019
novel coronavirus [2019-nCoV]) in Wuhan, China in December 2019, which is caused by …

Digital image watermarking using discrete wavelet transform and singular value decomposition

CC Lai, CC Tsai - IEEE Transactions on instrumentation and …, 2010 - ieeexplore.ieee.org
The main objective of developing an image-watermarking technique is to satisfy both
imperceptibility and robustness requirements. To achieve this objective, a hybrid image-…

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

…, H Yamaguchi, Q Ding, X Xie, JY Lang, CC Lai… - Nature cell …, 2008 - nature.com
The RAS–ERK pathway is known to play a pivotal role in differentiation, proliferation and
tumour progression. Here, we show that Erk downregulates Forkhead box O 3a (FOXO3a) by …

[HTML][HTML] IKKβ suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway

…, LY Li, B Ping, WC Huang, X He, JY Hung, CC Lai… - Cell, 2007 - cell.com
TNFα has recently emerged as a regulator linking inflammation to cancer pathogenesis, but
the detailed cellular and molecular mechanisms underlying this link remain to be elucidated. …

[HTML][HTML] Co-infections among patients with COVID-19: The need for combination therapy with non-anti-SARS-CoV-2 agents?

CC Lai, CY Wang, PR Hsueh - Journal of Microbiology, Immunology and …, 2020 - Elsevier
Co-infection has been reported in patients with severe acute respiratory syndrome (SARS)
and Middle East respiratory syndrome, but there is limited knowledge on co-infection among …

Anti-SARS coronavirus 3C-like protease effects of Isatis indigotica root and plant-derived phenolic compounds

CW Lin, FJ Tsai, CH Tsai, CC Lai, L Wan, TY Ho… - Antiviral research, 2005 - Elsevier
The 3C-like protease (3CL pro ) of SARS-coronavirus mediates the proteolytic processing of
replicase polypeptides 1a and 1ab into functional proteins, becoming an important target for …

Global epidemiology of coronavirus disease 2019 (COVID-19): disease incidence, daily cumulative index, mortality, and their association with country healthcare …

CC Lai, CY Wang, YH Wang, SC Hsueh, WC Ko… - International journal of …, 2020 - Elsevier
It has been 2 months since the first case of coronavirus disease 2019 (COVID-19) was
reported in Wuhan, China. So far, COVID-19 has affected 85 403 patients in 57 countries/…

[PDF][PDF] Erk associates with and primes GSK-3β for its inactivation resulting in upregulation of β-catenin

…, Y Li, Y Pan, Z Li, RC Bargou, J Qin, CC Lai… - Molecular cell, 2005 - cell.com
β-catenin is upregulated in many human cancers and considered to be an oncogene.
Hepatocellular carcinoma (HCC) is one of the most prevalent human malignancies, and …