Design and baseline characteristics of the stroke prevention by aggressive reduction in cholesterol levels (SPARCL) study

…, T Takahashi, M Kohno, TBJ Kuo, CM Chern… - Cerebrovascular …, 2003 - karger.com
Evidence suggests that statin therapy reduces the risk of stroke in patients with coronary heart
disease (CHD), but its benefit for patients with cerebrovascular disease and no history of …

Melatonin ameliorates neural function by promoting endogenous neurogenesis through the MT2 melatonin receptor in ischemic-stroke mice

CM Chern, JF Liao, YH Wang, YC Shen - Free Radical Biology and …, 2012 - Elsevier
Melatonin has many protective effects against ischemic stroke, but the underlying neuroprotective
mechanisms are not fully understood. Our aim was to explore the relationship between …

Preventive effect of silymarin in cerebral ischemia–reperfusion-induced brain injury in rats possibly through impairing NF-κB and STAT-1 activation

YC Hou, KT Liou, CM Chern, YH Wang, JF Liao… - Phytomedicine, 2010 - Elsevier
Silymarin and silibinin are bioactive components isolated from Silybum marianum. They
have been reported to exhibit anti-oxidative and anti-inflammatory effects. Many studies …

[HTML][HTML] Characterization of CADASIL among the Han Chinese in Taiwan: distinct genotypic and phenotypic profiles

YC Liao, CT Hsiao, JL Fuh, CM Chern, WJ Lee… - PloS one, 2015 - journals.plos.org
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
(CADASIL) is originally featured with a strong clustering of mutations in NOTCH3 exons 3–…

Frequency domain analysis of cerebral blood flow velocity and its correlation with arterial blood pressure

TBJ Kuo, CM Chern, WY Sheng… - Journal of Cerebral …, 1998 - journals.sagepub.com
We applied frequency domain analysis to detect and quantify spontaneous fluctuations in the
blood flow velocity of the middle cerebral artery (MCAFV). Instantaneous MCAFV of normal …

Salvianolic acid A alleviates ischemic brain injury through the inhibition of inflammation and apoptosis and the promotion of neurogenesis in mice

MY Chien, CH Chuang, CM Chern, KT Liou… - Free Radical Biology …, 2016 - Elsevier
Salvianolic acid A (SalA), a chemical type of caffeic acid trimer, has drawn great attention for
its potent bioactivities against ischemia-induced injury both in vitro and in vivo. In this study, …

Rehabilitation outcome in home-based versus supervised exercise programs for chronically dizzy patients

CL Kao, LK Chen, CM Chern, LC Hsu, CC Chen… - Archives of gerontology …, 2010 - Elsevier
We aimed to evaluate the effectiveness of vestibular rehabilitation (VR) exercise between
supervised and home-based programs in young and senior age groups of patients with …

Balance improvement in patients with benign paroxysmal positional vertigo

WC Chang, YR Yang, LC Hsu, CM Chern… - Clinical …, 2008 - journals.sagepub.com
Objective: To investigate the effect of an additional vestibular stimulated exercise programme
on balance for patients with benign paroxysmal positional vertigo. Design: Randomized …

Transfer function analysis of cerebral hemodynamics in patients with carotid stenosis

…, WJ Wong, YO Luk, CM Chern… - Journal of Cerebral …, 1999 - journals.sagepub.com
This study evaluates the validity of the transfer function analysis of spontaneous fluctuations
of arterial blood pressure (ABP) and blood flow velocity of the middle cerebral artery (MCAFV…

Andrographolide inhibits PI3K/AKT-dependent NOX2 and iNOS expression protecting mice against hypoxia/ischemia-induced oxidative brain injury

CM Chern, KT Liou, YH Wang, JF Liao, JC Yen… - Planta …, 2011 - thieme-connect.com
This study aimed to explore the mechanisms by which andrographolide protects against
hypoxia-induced oxidative/nitrosative brain injury provoked by cerebral ischemic/reperfusion (CI/…