Reduced microvascular thrombosis and improved outcome in acute murine stroke by inhibiting GP IIb/IIIa receptor-mediated platelet aggregation.

…, BL Hoh, HG Zerwes, CJ Prestigiacomo… - The Journal of …, 1998 - Am Soc Clin Investig
Treatment options in acute stroke are limited by a dearth of safe and effective regimens for
recanalization of an occluded cerebrovascular tributary, as well as by the fact that patients …

Exacerbation of cerebral injury in mice that express the P-selectin gene: identification of P-selectin blockade as a new target for the treatment of stroke

ES Connolly Jr, CJ Winfree, CJ Prestigiacomo… - Circulation …, 1997 - Am Heart Assoc
There is currently a stark therapeutic void in the treatment of evolving stroke. Although P-selectin
is rapidly expressed by hypoxic endothelial cells in vitro, the functional significance of P-…

Matrix metalloproteinase-9 in cerebral aneurysms

…, M Singh, J Huang, CJ Prestigiacomo, CJ Winfree… - …, 1997 - journals.lww.com
OBJECTIVE: Generalized disruption of arterial wall morphological changes in patients
harboring cerebral aneurysms has been documented; however, little is known regarding the …

CD18-mediated neutrophil recruitment contributes to the pathogenesis of reperfused but not nonreperfused stroke

CJ Prestigiacomo, SC Kim, ES Connolly Jr, H Liao… - Stroke, 1999 - Am Heart Assoc
Background and Purpose—Neutrophil (PMN) recruitment mediated by increased
expression of intercellular adhesion molecule-1 expression (ICAM-1, CD54) in the cerebral …

[HTML][HTML] Flow diverters for intracranial aneurysms

…, D Shastri, T Kass-Hout, CJ Prestigiacomo… - Stroke research and …, 2014 - hindawi.com
Flow diverters (pipeline embolization device, Silk flow diverter, and Surpass flow diverter)
have been developed to treat intracranial aneurysms. These endovascular devices are placed …

Initial hospital management of patients with emergent large vessel occlusion (ELVO): report of the standards and guidelines committee of the Society of …

…, PM Meyers, CJ Prestigiacomo… - Journal of …, 2017 - jnis.bmj.com
Objective To summarize the current literature regarding the initial hospital management of
patients with acute ischemic stroke (AIS) secondary to emergent large vessel occlusion (ELVO…

Analysis of the readability of patient education materials from surgical subspecialties

…, M Setzen, PW Carmel, CJ Prestigiacomo… - The …, 2014 - Wiley Online Library
Objectives/Hypothesis Patients are increasingly using the Internet as a source of information
on medical conditions. Because the average American adult reads at a 7th‐ to 8th‐grade …

Blood pressure management after endovascular therapy for acute ischemic stroke: the BEST-II randomized clinical trial

EA Mistry, KW Hart, LT Davis, Y Gao, CJ Prestigiacomo… - Jama, 2023 - jamanetwork.com
Importance The effects of moderate systolic blood pressure (SBP) lowering after successful
recanalization with endovascular therapy for acute ischemic stroke are uncertain. Objective …

Head, neck, and brain tumor embolization guidelines

EJ Duffis, CD Gandhi, CJ Prestigiacomo… - Journal of …, 2012 - jnis.bmj.com
Background Management of vascular tumors of the head, neck, and brain is often complex
and requires a multidisciplinary approach. Peri-operative embolization of vascular tumors …

Improving medical student recruitment into neurological surgery: a single institution's experience

…, IO Norrmén-Smith, KL Tomei, CJ Prestigiacomo… - World neurosurgery, 2013 - Elsevier
Objective Neurological surgery is historically among one of the most competitive residency
matches, but data suggest a downward trend in neurosurgical residency applicants in the …