This review describes the role of bone cells and their surrounding matrix in maintaining bone
strength through the process of bone remodeling. Subsequently, this work focusses on how …

Medicine today faces the combined challenge of an increasing number of untreatable diseases
and fewer drugs reaching the clinic. While pharmaceutical companies have increased …

Stromal-derived factor-1 (SDF-1) is a critical chemokine for endothelial progenitor cell (EPC)
recruitment to areas of ischemia, allowing these cells to participate in compensatory …

Biological applications of microfluidics technology is beginning to expand beyond the original
focus of diagnostics, analytics and organ-on-chip devices. There is a growing interest in …

Several computational models based on experimental techniques and theories have been
proposed to describe cytoskeleton (CSK) mechanics. Tensegrity is a prominent model for …

… A 1-cm-thick main plate machined in Al with a cut-out for the adapter plate completes the
setup. The adapter plate and main plate are screwed together using 6 screws. The main plate …

… To seed, 120,000 cells in 30 μL BM (∼110,000 cells/cm 2 ) were injected through the inlet
in the bioreactor and incubated for 1 h without flow to attach. Subsequently, either OIM or SM …

… The patch (∼20 cm 2 ) was manually positioned on the volunteer's forearm with gentle
pressure. The adhesive characteristics of the sTPE soft block component have shown to provide …

… A mold was machined from Plexiglas to create rectangular flow channel of 2 mm in width
and 2 cm in length. The channel was designed to have two different heights over its length, thus …

The ability to model the mechanical responses of different cell types presents many opportunities
to tissue engineering research to further identify changes from physiological conditions …