OBJECTIVE: Intermittent stimulation of the left cervical vagus nerve trunk is emerging as a
novel adjunct in the treatment of medically refractory seizures. We sought to evaluate …

Objective To demonstrate the safety and effectiveness of responsive stimulation at the seizure
focus as an adjunctive therapy to reduce the frequency of seizures in adults with medically …

Introduction The clinical results for the RNS System (NeuroPace, Mountain View, California,
USA) closed-loop responsive neurostimulator for the treatment of medically intractable …

… Christi Heck: drafting/revising the manuscript, study concept or design, analysis or interpretation
… CN Heck reports grant support from Neuropace. Go to Neurology.org for full disclosures. …

Objectives: To determine the relative magnitudes of neuron-specific enolase (NSE) levels
after complex partial status epilepticus (SE), absence SE, generalized convulsive SE, and …

… Heck has received research support from Boston Scientific and Neuropace. Dr. Sperling has
received research support from NIH, UCB Pharma, Eisai, Vertex Pharmaceuticals, Marinus, …

Neuron-specific enolase (NSE) is a sensitive marker of brain damage in stroke, global
ischemia, and coma. Serum NSE is also correlated with the duration and outcome of status …

Objective Patients with suspected mesial temporal lobe ( MTL ) epilepsy typically undergo
inpatient video–electroencephalography ( EEG ) monitoring with scalp and/or intracranial …

Purpose: To determine whether complex partial status epilepticus (CPSE) causes brain injury
in humans. Serum neuron‐specific enolase (s‐NSE) is an accepted marker of acute brain …

Objective The RNS System is a direct brain‐responsive neurostimulation system that is US
Food and Drug Administration–approved for adults with medically intractable focal onset …