Genetic variants associated with phenytoin-related severe cutaneous adverse reactions

…, TH Wang, SS Chuang, SF Tsai, CJ Chang, YS Chang… - Jama, 2014 - jamanetwork.com
Importance The antiepileptic drug phenytoin can cause cutaneous adverse reactions, ranging
from maculopapular exanthema to severe cutaneous adverse reactions, which include …

Factors affecting graft infection after cranioplasty

…, JT Yang, MH Lee, TC Wang, CN Chang - Journal of clinical …, 2008 - Elsevier
The aim of this study was to identify the risk factors associated with bone grafts infection after
cranioplasty. Eighty-four cranioplasties were performed on 75 patients between 2002 and …

A phase I/II clinical trial investigating the adverse and therapeutic effects of a postoperative autologous dendritic cell tumor vaccine in patients with malignant glioma

CN Chang, YC Huang, DM Yang, K Kikuta… - Journal of clinical …, 2011 - Elsevier
Previous clinical trials of dendritic cell (DC)-based immunotherapy in patients with
glioblastoma multiforme (GBM) have reported induction of systemic immune responses and …

The expectant treatment of “asymptomatic” supratentorial epidural hematomas

TY Chen, CW Wong, CN Chang, TN Lui… - …, 1993 - journals.lww.com
SEVENTY-FOUR PATIENTS WITH a traumatic epidural hematoma (EDH) and a Glasgow
Coma Scale score of more than 12 received expectant treatment; 14 subsequently underwent …

Optic nerve decompression in fibrous dysplasia: indications, efficacy, and safety

YR Chen, A Breidahl, CN Chang - Plastic and reconstructive …, 1997 - journals.lww.com
: Optic nerve decompression is controversial in posttraumatic visual loss and as a prophylactic
therapy in fibrous dysplasia involving the optic canal. It is less controversial for the …

Stereotactic brain biopsy: Single center retrospective analysis of complications

CC Chen, PW Hsu, TWE Wu, ST Lee, CN Chang… - Clinical neurology and …, 2009 - Elsevier
OBJECTIVE: Stereotactic biopsy is a widely used surgical technique for the histological
diagnosis of intracranial lesions. Potential risks of this procedure, such as hemorrhage, seizure, …

Blood oxygenation level‐dependent MRI of cerebral gliomas during breath holding

YY Hsu, CN Chang, SM Jung, KE Lim… - Journal of Magnetic …, 2004 - Wiley Online Library
Purpose To assess the cerebrovascular responses to short breath holding of cerebral gliomas
using blood oxygenation level‐dependent (BOLD) magnetic resonance imaging (MRI). …

Clinical features and surgical outcome of clinical and subclinical pituitary apoplexy

ZH Liu, CN Chang, PC Pai, KC Wei, SM Jung… - Journal of clinical …, 2010 - Elsevier
The clinical features of pituitary hemorrhage vary from asymptomatic to catastrophic. Clinical
symptomatic pituitary apoplexy is a well-described syndrome characterized by sudden …

Prophylactic anticonvulsants for prevention of immediate and early postcraniotomy seizures

ST Lee, TN Lui, CN Chang, WC Cheng, DJ Wang… - Surgical neurology, 1989 - Elsevier
Phenytoin (15 mg/kg) was administered intravenously to 189 patients shortly before their
intracranial, supratentorial surgery was completed. Intravenous phenytoin of 5–6 mg/kg/day in …

Sleep deprivation inhibits expression of NADPH-d and NOS while activating microglia and astroglia in the rat hippocampus

JC Hsu, YS Lee, CN Chang, HL Chuang, EA Ling… - Cells Tissues …, 2003 - karger.com
This study investigated the expression of nitric oxide (NO)-synthesizing enzymes and the
glial reaction in the rat hippocampal formation following sleep deprivation for 5 days. …